ID H3AQ56_LATCH Unreviewed; 997 AA.
AC H3AQ56;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Espin like {ECO:0000313|Ensembl:ENSLACP00000011777.1};
GN Name=ESPNL {ECO:0000313|Ensembl:ENSLACP00000011777.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000011777.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000011777.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, stereocilium
CC {ECO:0000256|ARBA:ARBA00004645}.
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DR EMBL; AFYH01137694; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01137695; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01137696; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01137697; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01137698; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01137699; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01137700; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01137701; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01137702; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3AQ56; -.
DR STRING; 7897.ENSLACP00000011777; -.
DR Ensembl; ENSLACT00000011867.1; ENSLACP00000011777.1; ENSLACG00000010368.1.
DR eggNOG; KOG0504; Eukaryota.
DR GeneTree; ENSGT00940000156970; -.
DR HOGENOM; CLU_017253_0_0_1; -.
DR InParanoid; H3AQ56; -.
DR OMA; PEENENW; -.
DR TreeFam; TF326392; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
DR GO; GO:0007605; P:sensory perception of sound; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24153; ESPIN; 1.
DR PANTHER; PTHR24153:SF0; ESPIN-LIKE PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 2.
DR SMART; SM00248; ANK; 6.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Hearing {ECO:0000256|ARBA:ARBA00022740};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 103..135
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 238..263
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 331..375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 702..726
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 754..782
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 334..351
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..375
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 768..782
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 997 AA; 112398 MW; 46836D81DF8EFDE5 CRC64;
MALHRALQAA KNGDLQTLRS LQAGGSLAAD IADSQGATLV HYTARTGKLD CLKFLVAEAN
FPGNKKARNG ASPAHDAAAT GNLMELQWLI GRGGCHIQDP DASGASVLHL AARFGRCETV
RWLLEAGCDA MMETESGAIP AHYAAAKGDL TCLKLLVTQA PSRNNIFFRG GAADIYIKCI
KIHTHTPLSL RWRSGRCLHR KATSNTSSLH FPACKNIIPA LRYVASFTGI DLSAQDNEGA
TALHFAARAG HFRILERLLR MGAKSITDYW GGTPLHDAAE NGELECCQFL ILSKVLPGLR
DQDGYMAGDL AEYNGHSQCA KYLRTAEKLN PVTVQPSSPP PFAPPLPPQG EPFLASQQES
HQTLETNHTN PKASNMTAES WEAHVDESDP TLATAGPCTF RVRCQVLSSR GGELTPLRSE
QKENGIVPLP VDEVNMVDVD VLVPTHDERG RTIPEWKRQV MVRKLQARLL DEEEQRKKYN
GAQGNDYIKM EGWRYSHAHN AILGPFGEFL TEDDLIYLEK QIANVRTKEK DQDYASELDR
LAEELRTILP APIVNITVNT QFLQQNAGKD GHLSLPVWCN RISGIVKSMS LLLTNVNDRE
KGDHENKISK MPNSELASVF SQRPENRGSI RTREKVEKEI NRFGVSVRNL RSNFERRRNL
EGETSAFEHV DVQYGDATEY QQDYIDEKQN VYMTNTEDLE YTSDSGISSE ETSADQSTSP
APLTESTSLR KERIVVLFLS HWKKSTYTMS LRTKTKTSDE ASTDVESEME TNQKTQSQQS
MENGRLSHFF QQKRTITKLI GNWRNIICHV PSRQLRRLNR QQITYSPEQF LPRVNGAPID
YKSLTLDLFM LGYFHILELD LTRDERKMRH LLCFEVFDHL GRFSWETVRE FHKTVIDEID
AGKREWKDGF EDIKQRFFGN SEDSAMAADT TKQQQPIVTR PVPKVIVQSA TPEENENWAT
TDSFDLGNFS NDEICKYIDR SFAFWKEKEA EMFDFEE
//
