ID H3ARB0_LATCH Unreviewed; 616 AA.
AC H3ARB0;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=F-box and WD repeat domain containing 7 {ECO:0000313|Ensembl:ENSLACP00000012181.1};
GN Name=FBXW7 {ECO:0000313|Ensembl:ENSLACP00000012181.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000012181.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000012181.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AFYH01156991; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01156992; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01156993; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01156994; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01156995; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01156996; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01156997; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01156998; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01156999; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01157000; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3ARB0; -.
DR Ensembl; ENSLACT00000012273.1; ENSLACP00000012181.1; ENSLACG00000010721.2.
DR GeneTree; ENSGT00940000154986; -.
DR HOGENOM; CLU_000288_103_7_1; -.
DR OMA; AMVPWED; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000010721; Expressed in post-anal tail muscle and 6 other cell types or tissues.
DR GO; GO:0043170; P:macromolecule metabolic process; IEA:UniProt.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:UniProt.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR CDD; cd22133; F-box_FBXW7; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19849:SF1; F-BOX_WD REPEAT-CONTAINING PROTEIN 7; 1.
DR PANTHER; PTHR19849; PHOSPHOLIPASE A-2-ACTIVATING PROTEIN; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00320; WD40; 8.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50181; FBOX; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 5.
DR PROSITE; PS50082; WD_REPEATS_2; 7.
DR PROSITE; PS50294; WD_REPEATS_REGION; 6.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..616
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003579862"
FT DOMAIN 188..234
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT REPEAT 300..325
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 326..365
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 366..405
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 406..445
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 446..485
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 486..525
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 529..568
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 616 AA; 68782 MW; B0405DB5240DB7F3 CRC64;
RIGLLVSLIC CDSGVLLLVL LPDLPFTCLS MSTLDTVSYL PEGVLHCQRL ASIQTHGTLG
STETMGFYGT LKMIFYKMKR KLDHGPEVRS FSSGKKPCKG SEYTSTTGLV PCSATPTTFG
DLRAANGQGQ QRRRIPSIPP PTGLQEWLRM FQSWSGPEKL LALDELIDSC EPTQVKHMMQ
VIEPQFQRDF ISLLPKELAL YVLSFLEPKD LLQAAQTCRY WRILAEDNLL WREKCKEEGI
DEPLQIKRRK VIKRGELKSP KKIIYLFICE ISNWTSNKLK AMQVLKGHDD HVITCLQFCG
NRIVSGSDDN TLKVWSAVTG KCLRTLVGHT GGVWSSQMRD NIIISGSTDR TLKVWNAETG
ECIHTLYGHT STVRCMHLHE KRVVSGSRDA TLRVWDIETG QCLHVLMGHV AAVRCVQYDG
RRVVSGAYDF MVKVWDPETE TCLHTLQGHT NRVYSLQFDG IHVVSGSLDT SIRVWDVESG
NCIHTLTGHQ SLTSGMELKD NILVSGNADS TVKIWDIKTG QCLQTLQGPN KHQSAVTCLQ
FNKNFVITSS DDGTVKLWDL KTGEFIRNLV TLESGGSGGV VWRIRASNTK LVCAVGSRNG
TEETKLLVLD FDVDMK
//
