ID H3ART1_LATCH Unreviewed; 464 AA.
AC H3ART1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=FCP1 homology domain-containing protein {ECO:0000259|PROSITE:PS50969};
GN Name=CTDSPL2 {ECO:0000313|Ensembl:ENSLACP00000012352.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000012352.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000012352.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Probable phosphatase. {ECO:0000256|ARBA:ARBA00037324}.
CC -!- SIMILARITY: Belongs to the CTDSPL2 family.
CC {ECO:0000256|ARBA:ARBA00038355}.
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DR EMBL; AFYH01104515; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01104516; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01104517; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01104518; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01104519; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01104520; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01104521; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01104522; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005999751.1; XM_005999689.2.
DR RefSeq; XP_005999752.1; XM_005999690.2.
DR AlphaFoldDB; H3ART1; -.
DR Ensembl; ENSLACT00000012445.1; ENSLACP00000012352.1; ENSLACG00000010876.1.
DR GeneID; 102360498; -.
DR KEGG; lcm:102360498; -.
DR CTD; 51496; -.
DR GeneTree; ENSGT01040000240503; -.
DR HOGENOM; CLU_034042_4_0_1; -.
DR OrthoDB; 5473812at2759; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000010876; Expressed in pectoral fin and 6 other cell types or tissues.
DR GO; GO:0016791; F:phosphatase activity; IEA:InterPro.
DR CDD; cd07521; HAD_FCP1-like; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR011948; Dullard_phosphatase.
DR InterPro; IPR004274; FCP1_dom.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR NCBIfam; TIGR02251; HIF-SF_euk; 1.
DR PANTHER; PTHR12210:SF173; CTD SMALL PHOSPHATASE-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR12210; DULLARD PROTEIN PHOSPHATASE; 1.
DR Pfam; PF03031; NIF; 1.
DR SMART; SM00577; CPDc; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR PROSITE; PS50969; FCP1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 281..440
FT /note="FCP1 homology"
FT /evidence="ECO:0000259|PROSITE:PS50969"
FT REGION 1..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..77
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..118
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 464 AA; 52230 MW; B0ED8D5CB3F0096E CRC64;
MRLRTRKASQ QSSPAHSQRA SRTKRKHSDV DDDAPAGGEA QKSETGLLSS IKKFIRGSAP
KVEQENPAKR SRIERDLDNN LITSTPRTDE KPNKSLSRVR RKSQVNGEAG NYNANKHTKQ
NGKLEDNTEA GSPPRTTLLG TIFSPVFNFF SPASKNGTSG SDSPGQAVEA EEIVKQLDME
QVDEITTSTA TSTNGAVYSS QPAPVRCAVD NGSEVVVNSA DRDLPPLTAP VSPDSGYSSA
HAEATYEEDW EVFDPYYFIK HVPPLTEEQL NRKPALPLKT RSTPDFSLVL DLDETLVHCS
LNELEDAALT FPVLFQDVIY QVYVRLRPFF REFLERMSQI YEIILFTASK KVYADKLLNI
LDPKKQLVRH RLFREHCVCV QGNYIKDLNI LGRDLSKTII IDNSPQAFAY QLSNGIPIES
WFMDKNDNEL LKLVPFLEKL VELNEDVRPH ISERFRLHDM LPPD
//
