ID H3ASG2_LATCH Unreviewed; 621 AA.
AC H3ASG2;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Plastin 1 {ECO:0000313|Ensembl:ENSLACP00000012583.1};
GN Name=PLS1 {ECO:0000313|Ensembl:ENSLACP00000012583.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000012583.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000012583.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AFYH01135243; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01135244; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3ASG2; -.
DR STRING; 7897.ENSLACP00000012583; -.
DR Ensembl; ENSLACT00000012677.1; ENSLACP00000012583.1; ENSLACG00000011086.1.
DR eggNOG; KOG0046; Eukaryota.
DR GeneTree; ENSGT00950000183097; -.
DR HOGENOM; CLU_015284_2_0_1; -.
DR InParanoid; H3ASG2; -.
DR OMA; DDIIIKW; -.
DR TreeFam; TF300680; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0051017; P:actin filament bundle assembly; IEA:InterPro.
DR CDD; cd21323; CH_PLS1_rpt1; 1.
DR CDD; cd21326; CH_PLS1_rpt2; 1.
DR CDD; cd21332; CH_PLS1_rpt4; 1.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 4.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR039959; Fimbrin/Plastin.
DR PANTHER; PTHR19961; FIMBRIN/PLASTIN; 1.
DR PANTHER; PTHR19961:SF27; PLASTIN-1; 1.
DR Pfam; PF00307; CH; 4.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00033; CH; 4.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 2.
DR PROSITE; PS50021; CH; 4.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 17..52
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 57..92
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 128..244
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 272..376
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 395..504
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 516..621
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
SQ SEQUENCE 621 AA; 69976 MW; 6B3B837B0A1FAD19 CRC64;
QLYSQNMANN TTTISREELE DLREAFNKID IDNSGYVSDY ELQDLFKEAN LPLPGYKVRE
IVEKIIAAAD NNKDGKISFE EFVSVFQELK SKEISKTFRM LINRKEGITA IGGTSAISSE
GTQHSYSEEE KVAFVNWINK ALEGDPDCKH VVPMDPTNES FFKSVGDGIL LCKMINLSQP
DTIDERVINK KKLTPFTISE NLNLALNSAS AIGCTVVNIG SLDLKEGRPH LVLGLLWQII
KVGLFAEIEL SKNEALIALL GEGEDLEQLL KLSPEELLLR WVNYHLDNAG WEKISNFSSD
IMDSKAYYHL LNQIAPKGDN IDEIFLQERD DLKRAEYMLE EAEKLGCKQF VTPKDVVAGN
PKLNMAFVAN LFNMYPALHK PENVDYDLAL LEGESREERT FRNWMNSLGV TPRVNHLYSD
LTDALVIFQL YERIRVPVDW SRVNKPPYPV LGCNMKKIEN CNYAVEHGKA KAKFSLVGIG
GQDLCDGNPT LTLALVWQLM RRYTLNVLSD LGEGEKVNDE IIIRWVNQTL ADANKTTFIS
SFKDKSISTS LPILDLIDAI APSAIREEMV KREDLSEADK LNNAKYAISV ARKIGARVYA
LPEDLLEVKP KMIMTVFACL M
//
