ID H3AU16_LATCH Unreviewed; 445 AA.
AC H3AU16;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSLACP00000013137.1};
GN Name=LOC102360326 {ECO:0000313|Ensembl:ENSLACP00000013137.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000013137.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000013137.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the C/M/P thioester hydrolase family.
CC {ECO:0000256|ARBA:ARBA00006538}.
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DR EMBL; AFYH01154463; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006004813.1; XM_006004751.2.
DR AlphaFoldDB; H3AU16; -.
DR STRING; 7897.ENSLACP00000013137; -.
DR MEROPS; S09.A51; -.
DR Ensembl; ENSLACT00000013233.1; ENSLACP00000013137.1; ENSLACG00000011570.1.
DR GeneID; 102360326; -.
DR KEGG; lcm:102360326; -.
DR eggNOG; ENOG502QQ8Z; Eukaryota.
DR GeneTree; ENSGT01010000222336; -.
DR HOGENOM; CLU_029849_4_0_1; -.
DR InParanoid; H3AU16; -.
DR OMA; CAHYEAD; -.
DR OrthoDB; 5356064at2759; -.
DR TreeFam; TF314911; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000011570; Expressed in muscle tissue and 4 other cell types or tissues.
DR GO; GO:0016790; F:thiolester hydrolase activity; IEA:InterPro.
DR GO; GO:0006637; P:acyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 2.60.40.2240; Acyl-CoA thioester hydrolase/BAAT N-terminal domain; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR016662; Acyl-CoA_thioEstase_long-chain.
DR InterPro; IPR014940; BAAT_C.
DR InterPro; IPR006862; Thio_Ohase/aa_AcTrfase.
DR InterPro; IPR042490; Thio_Ohase/BAAT_N.
DR PANTHER; PTHR10824:SF38; -; 1.
DR PANTHER; PTHR10824; ACYL-COENZYME A THIOESTERASE-RELATED; 1.
DR Pfam; PF08840; BAAT_C; 1.
DR Pfam; PF04775; Bile_Hydr_Trans; 1.
DR PIRSF; PIRSF016521; Acyl-CoA_hydro; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 43..175
FT /note="Acyl-CoA thioester hydrolase/bile acid-CoA amino
FT acid N-acetyltransferase"
FT /evidence="ECO:0000259|Pfam:PF04775"
FT DOMAIN 238..444
FT /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08840"
SQ SEQUENCE 445 AA; 49025 MW; E6F33D3042460404 CRC64;
MLYLSVSLRS LCMHRSRPFA LKACRSLHQS AKVTVSPKKS LADEKVKIQA SDLKPLQEVT
LRALVANEQG CLFDSCAHYQ ADDTGAVDLD RDPSRGGDYT GIEPMGLLWS LSPAQMEKPH
QRLQKREVMK SPMQVEVIVH RGYTNPGAIP GQVLAKAKAE RWFSGPGIRR VCLKEGRVRG
SLFLPPGDGP FPGVIDMFGD EGGLVEYRSS LLASRGFVSL ALPYLCFEDL PQTMSDFQLE
YFEDAVRFLQ RHPKVKDTGI GVIGTAKGAD LALSMASFLQ QVTATVCISG CSANTVADLH
YKDLTLPGLG YNVDRIRIMD NGVLDVSEAL DDPTELANVN SIIPIEKAQG PFLFVVGEED
HYWKSKFFAE QAIRRLKRHG KNNFQLLTYA GAGHRIDPPC SPFCLVDIDR VLGVPVLGGG
EAKSHAHAQM DSWGKIQDFL RMHLS
//
