ID H3AU46_LATCH Unreviewed; 2422 AA.
AC H3AU46;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Jumonji domain containing 1C {ECO:0000313|Ensembl:ENSLACP00000013167.1};
GN Name=JMJD1C {ECO:0000313|Ensembl:ENSLACP00000013167.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000013167.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000013167.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AFYH01087362; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01087363; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01087364; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01087365; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01087366; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01087367; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01087368; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01087369; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 7897.ENSLACP00000013167; -.
DR Ensembl; ENSLACT00000013263.1; ENSLACP00000013167.1; ENSLACG00000011597.2.
DR eggNOG; KOG1356; Eukaryota.
DR GeneTree; ENSGT00940000158210; -.
DR HOGENOM; CLU_228251_0_0_1; -.
DR InParanoid; H3AU46; -.
DR OMA; PNKTSKM; -.
DR TreeFam; TF324723; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000011597; Expressed in post-anal tail muscle and 6 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0032454; F:histone H3K9 demethylase activity; IEA:InterPro.
DR Gene3D; 2.60.120.650; Cupin; 1.
DR InterPro; IPR045109; JHDM2-like.
DR InterPro; IPR003347; JmjC_dom.
DR PANTHER; PTHR12549; JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN; 1.
DR PANTHER; PTHR12549:SF6; JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 2C-RELATED; 1.
DR Pfam; PF02373; JmjC; 1.
DR SMART; SM00558; JmjC; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51184; JMJC; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 2174..2380
FT /note="JmjC"
FT /evidence="ECO:0000259|PROSITE:PS51184"
FT REGION 147..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 504..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 771..792
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 875..898
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1002..1039
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1405..1427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1498..1578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1856..1946
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..202
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..278
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..317
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..349
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1007..1031
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1513..1565
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1856..1887
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1897..1928
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1929..1946
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2422 AA; 270132 MW; 6676F3069339E303 CRC64;
TFKPLIGKCM LNSVTAVEFF VDRQLDFVTE ESAFQPYQDE VDSLSPVLRD NPQLQEEVKA
WVKEQKVQEI FMQGGPYSLN GYRVRVYRQD SATQWFTGII THHDLFSRTM VVMNDQVLEP
QNVDPSMVQM TFLDDVVHSL LKGENIGITS RRRSRSNQTN NTAHGHYTRA QANSPRPAMN
SQTVTPKQNQ LPQQQQQQQQ QRNVRSHKRK GSDSSVPDED KTKEEKVDNM GRGEFSKTKN
KQIVKRRKPE EEEKKVDLKR PKEENALDCY ESSDSENSNK KLIDSSSEQN SENELKNMSA
SKSCEQEGES QCSEGAEETT LIDRHSPWDE IQEDEKACKA ERFQSADSEV EEKPPLQPVG
SPALHDQNIS TLGVQGCIAE TKTVELLPKE HSVCVSPTSE SGGDEKSLSE MAQENNNFSV
QAAQKLEFYG NDLKQSVETP GGSDKRDTEF GQHLDSSVIS KTDSVHSEVM KTVSVVNESP
AWTDQEKLHY GSVMPTVGAI SSEEGVKKLH KSTPSPDILK PKANTSPVIT KSKSGTCPDT
HKHKLSTSPD TLKPKANYQS SQAVSFTRAV SKIECELPRS SFHSVTARLR ATDVTKSPLI
IDKNEHFTVY RDPTLVGPEP EANHVSAYLH QHVHPLHAST HATCITPNTH HPTLSAPIAA
INAHLLSSAS HHHHPHLLQA VLPGVPPASL IGGHSRLDST HASNLSHLAQ AHHQQQQLLQ
HQSPHLLGQT HAAASYNQLG LYPIIWQYPN GTHPYPRLSL PSSKWVHPEN SMNTEASLRR
NTPSPWLHQP TPVSSADSLG LLSHIPVRPA STDLPRPLKL AMHSSPPLSK AAVDHHKEEM
EKKSFVEPLR SITPVPVKSD LDHSRSHIGK ESHLHRHFMD PGPSHNKKQR PLLETGDRQN
KYKEENRRIL QESIEVAPFT AKIKATEGGK DPYSRIVALP IISPKGQVLK QEKDVERSVE
DLFKLKHALQ TLPQSNYFTT LSNSVVNEPP QSYPSKEAAN LYGEKHSGNP SMVSSPQSVT
SFNSKSLSKP PPLIKHQSEG EGLVGKITEQ LSQQVASHTV NSNNIDCRNS TQLSVSPLNP
LRSMPALHRA PVFHPPIQQN LERKESNYGS LSPPMLTPVQ PVNAAGKLAE SQKPPTLIPE
LKDINSTYKI NHEMISLEIH KGSDTVSHEK SEWHLEKRNG KPQAATASVI VRPPSSMKYD
SVPVTQSASK DPVSERLLTE TNHMDCLKTT EARETGSVIL PNINSISTCT PYGKHFQAFS
QGNFPSSVIA AASIMCSIKT EVTTSATTTT SVLSQGGSDV TYSVLASPRQ ESATPRTVLH
SAAQSQECKV STTATTDFLP INTKTGTTAQ AISGGSKITD FIHLKKHKAA LAAAQSRSTN
SNENEPATAK VQKCSGIISH DSTAVSSTTN KANSVSNGQS AQLTQPNYHT KLKKAWLTRH
SEEDKNTNKV EKIESTVSEI IKPCSVNLIA STSNEVENSK ILEEKAVKED KITKKGTKRT
FESGSESDDS DESESKSEQR AKRQPKPTYK KKQNDLQKKR SDAEKEEEEI RPNGILSRSA
KEKSKLKLQN SNTSNGIPRS VLKDWRKVKR LKQTGESFLQ DDSCSEIGPN LQKCRECRMV
RNKKAEEPTH SPVFCRFYYF RRLSFSKNGV VRIDGFSSPD QYDEEALSLW TPDDSEENEL
DMDTCKYILD NIGDKFCQLV MSEKTAMSWV KKDAKIAWKR AVRGVREMCD ACEATLFNIH
WVCQKCGFVA CLDCYKAKER KSSRDKELYA WMKCVKGQPH DHKHLMPTQI IPGSVLTDLV
EAMHTLREKF GIKSHCLCSN KPSIQCGKLP VTNGVSQVLQ NVLNHSNKIS LCLPESQQSA
TQKPEMNGSV SPGSNKSTDS KLTPPESQSP LHWLADLAEQ KSREEKKENK GSSLDKQMEE
RDQADRTESL SCKASPPVSH SCEQGSTLRD LLTTTAGKLR LGSTDAGIAF APVYSSGNSA
CKGGRNMPNI LDDIIASVVE NKIPAKQMPK LNLKVDQKEE TKNCKKSALD EYNKLHSDIP
HSWLCDKRLL WLKDHKNRRN MNIFRDCWRR GLPVLVSGVH KKMNSNLWKA ELISQEFGDQ
QADLLDCKDG IISNANIKEF WDGFEDITKR PKVKSGETVV LKLKDWPSGE DFRVMMPSRY
DDFMKMLPLP EYSNPEGNLN LASYLPGFFV RPDLGPRMCS AYGVAAAKDQ ETGTTNLHVE
VSDILNILVY VGVARGNGVL SKTGVFKKLE EEDLDDLIKR RLKDSSETPG ALWHIFDSKD
IEKIHELLQK VAKEQGLDVP PEHDPIRDQS WYLNKKLRER LLEEYGVKTL TVVQFLGDAV
ILPAGTLHQV QNLHSCIQVI EEFVSPEHLV ESFHLTQELR PSKDEINYDD KLQVKNILYH
SVKEAVGALK VHEEEMENTE EN
//
