ID   H3AWU8_LATCH            Unreviewed;       282 AA.
AC   H3AWU8;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 2.
DT   27-MAR-2024, entry version 52.
DE   SubName: Full=Sprouty RTK signaling antagonist 4 {ECO:0000313|Ensembl:ENSLACP00000014119.2};
GN   Name=SPRY4 {ECO:0000313|Ensembl:ENSLACP00000014119.2};
OS   Latimeria chalumnae (Coelacanth).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Coelacanthiformes; Coelacanthidae; Latimeria.
OX   NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000014119.2, ECO:0000313|Proteomes:UP000008672};
RN   [1] {ECO:0000313|Proteomes:UP000008672}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT   "The draft genome of Latimeria chalumnae.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLACP00000014119.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the sprouty family.
CC       {ECO:0000256|ARBA:ARBA00010964}.
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DR   EMBL; AFYH01139616; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; H3AWU8; -.
DR   STRING; 7897.ENSLACP00000014119; -.
DR   Ensembl; ENSLACT00000014218.2; ENSLACP00000014119.2; ENSLACG00000012427.2.
DR   eggNOG; ENOG502QQ4V; Eukaryota.
DR   GeneTree; ENSGT00950000183055; -.
DR   HOGENOM; CLU_077696_0_0_1; -.
DR   InParanoid; H3AWU8; -.
DR   OMA; MCLVQGV; -.
DR   TreeFam; TF325070; -.
DR   Proteomes; UP000008672; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0009966; P:regulation of signal transduction; IEA:InterPro.
DR   InterPro; IPR007875; Sprouty.
DR   PANTHER; PTHR12365:SF6; PROTEIN SPROUTY HOMOLOG 4; 1.
DR   PANTHER; PTHR12365; SPROUTY; 1.
DR   Pfam; PF05210; Sprouty; 1.
DR   PROSITE; PS51227; SPR; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT   REGION          82..122
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        82..98
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   282 AA;  31332 MW;  197B5A4B82CB9ADC CRC64;
     MVQPLLDSRI PYGRLQHPLT ILPIDQMKTT HIENDYIDNP LVAQQVSQKH SRGHHETAVI
     NQHLQRCDHH DITHPWISFS GRPSSISSSS STSSDQRLLD HVAPPPVADQ SSPRTVRAQP
     KSMKCKPLDL KSPLPQEIDK HFLLCEGCGK CKCMECTSPR TLPSCWVCNQ ECLCSAQNLV
     NYTTCMCLVK GIFYHCTNED NEGSCADHPC SCSHSNCCSR WSFMGALSLV LPCLLCYLPA
     TGCVKLSQKC YDKVSRPGCR CKNTNSVCKA QEGKPSSQEK PS
//