ID H3AX43_LATCH Unreviewed; 630 AA.
AC H3AX43;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Kelch repeat and BTB domain containing 12 {ECO:0000313|Ensembl:ENSLACP00000014214.1};
GN Name=KBTBD12 {ECO:0000313|Ensembl:ENSLACP00000014214.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000014214.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000014214.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AFYH01040369; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01040370; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01040371; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3AX43; -.
DR STRING; 7897.ENSLACP00000014214; -.
DR Ensembl; ENSLACT00000014314.1; ENSLACP00000014214.1; ENSLACG00000012517.1.
DR eggNOG; KOG4441; Eukaryota.
DR GeneTree; ENSGT00940000156836; -.
DR HOGENOM; CLU_004253_14_6_1; -.
DR InParanoid; H3AX43; -.
DR OMA; DYWRDGP; -.
DR TreeFam; TF351656; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000012517; Expressed in post-anal tail muscle and 4 other cell types or tissues.
DR CDD; cd18485; BACK_KBTBD12; 1.
DR CDD; cd18276; BTB_POZ_KBTBD12; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR PANTHER; PTHR24412:SF459; KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 12; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 2.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 3.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 33..100
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 630 AA; 71631 MW; 9E597E4F3CDB5451 CRC64;
MDCNTAGVPS ARTKHSLNLL DQVSRMKESV EMIDVVLVAE GKKFPCHRLI LAAFSPYFKA
MFSCGLLECS KQEVELHDTT AESLSAILNY MYSSDLHLSN STVQGIAMTA FFLQMEDIFL
VCQRYMIDHM DASNCTGIYY FAKHLGAEEL SEEAKKYLYK HFSEVCLHEE VLEIEAHQIL
DLIQSDDLNV SREESILDLV LRWVNHSRKS RVQHLLDLLK QVRLVLVSPA FLQEALKRNT
ILLSSADCHR LIEVALEDIK KTRTPQPLHL RYGMETTDLL LCIGNNAMGI KSRHGSYANA
SFCYDPSRRK TYFITSPNYG EALGYISTGV VMENNDIIVA GEAGVTKKAR QKTKHVEIYR
YHIRGSHFWE KLCAAEFREL YALGTIHSDL YVLGGQMKMK NQYLITNCVD KYAVDGDHWR
SVAPLPLPLA CHAVVTLNNK LYVMGGWTPQ MDFPDEEPDR LNSKLFQYDP GRDRWTMCAP
MKYSKYRFST AVLNSEIYVL GGIGCYGLDR GQARRCLDAV EIYNPDGDFW REGPALPSPL
LSLRTNSTNT GVLEGNLYLC GGYYGADRHE VIHKDILELN PWENQWNVVA HNVLMHDSYD
VCLVARLNPR DLIPPPSDLL DQDDVHTSRQ
//
