ID H3AYL6_LATCH Unreviewed; 1124 AA.
AC H3AYL6;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Cilia and flagella associated protein 70 {ECO:0000313|Ensembl:ENSLACP00000014737.1};
GN Name=CFAP70 {ECO:0000313|Ensembl:ENSLACP00000014737.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000014737.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000014737.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AFYH01043273; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01043274; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3AYL6; -.
DR Ensembl; ENSLACT00000014840.1; ENSLACP00000014737.1; ENSLACG00000012971.2.
DR GeneTree; ENSGT00390000013319; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR44314; CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70; 1.
DR PANTHER; PTHR44314:SF1; CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70; 1.
DR Pfam; PF12895; ANAPC3; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 931..964
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 965..998
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1002..1035
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 836..886
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 865..882
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1124 AA; 126903 MW; B624906619A1E340 CRC64;
AENKPRSPVP VQVTVLRGRY LKGTKSDAPV TYVRAEFNGT LLGDSPKLEA SPETGVEYNF
TSSFDCNFEG QNNLDDIAHK PFILTIVEIL PKERKQKEEK TAVLAQATVD LLPLLQGECT
FKTTVTLHAV ATASVETTRQ DAPKPILEVA VFVPEPLLTE YQIEGSNLLK VTVEVAYSVP
EAWNITGPQF NTVVSLQVPA SSEKECILTF PNGILKPGGE KEPTPRQKKW PTSNILAPGA
HCIPESFIHS SSYDEEDGDL NRESKEFRLE AETEKKRVVW DFERRCFLEP DAVITLRKRI
AECRYWPVEI TRSLIPTFVK GKAIRAEKGD DDSQLSSHGV AYVNMAPLLY PGVKQIRGAY
QIVAYNETEI FEKTKQLNSV VREVACQFSV VGKPQAPAAS GLPHPKVVPS KTLREEKGVK
EPMQQNSALL KLPISESLTE METHASQNVE GLQYVEAKSY ILLEFALEKP LVPKRPPEEL
AKRVQDLIPP RPAVPRRYGG AQKAVKGYHS QISSIASTIL DEYHYMFGQQ IVEGRPLNSQ
TLEEQKRKLN YELNFSGKYF AFKEQLKHSV VKIVREKYLK TTAFEDREEL QAFLSELYIY
LVDQMHIALN KTLVADTPEP VPDILADYTQ LKHFAREAEI NEEFDLAAKY YQEILARDRN
NPDHWFDYGT FCLLISDDGK AEECFHEAVA LNQNHLPSLL LSGIMAMARE KYEEAETYLE
DTTCVDSRSV VAWTILGLFY ELQDNVIRAE MAFLEANKQL QVAATALAAQ QLEEDAKVDS
IEKGERREKK HNSLVFWSSL DMGLDALKLE QIRVPKEGDG VLEGATDLSL STALDLPEPL
NNKHPTGKAV VGSHKSHTTI TSKSKKTPHK VEQSDQRMSS LHEQKQLESV QQPTRSIFME
TAHFLLHANA LQAVERVLAH ELLCQEKDPT SEYYVALAQV YLQQKNFPKA QEKLQKAVKI
DHQNPDVWAL TGHLYYLTQR YTDAKECYEH TVDLVKDASE MHPVYVRLGS IYIQEEEYEK
AKHSYLVACK KSPTCLSWLG VGVACYRLGE VTEAEDALSE ANILNNSNPE VWGYLTLVCL
QKTGRQFEAE QSYKYAAKLN LKNQMLLREI EELQQMVGFG NPAF
//
