ID H3AZ19_LATCH Unreviewed; 420 AA.
AC H3AZ19;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Transmembrane protein 165 {ECO:0000313|Ensembl:ENSLACP00000014890.1};
GN Name=TMEM165 {ECO:0000313|Ensembl:ENSLACP00000014890.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000014890.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000014890.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the GDT1 family.
CC {ECO:0000256|ARBA:ARBA00009190}.
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DR EMBL; AFYH01120349; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01120350; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01120351; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01120352; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01120353; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3AZ19; -.
DR STRING; 7897.ENSLACP00000014890; -.
DR Ensembl; ENSLACT00000014994.1; ENSLACP00000014890.1; ENSLACG00000013104.1.
DR eggNOG; KOG2881; Eukaryota.
DR GeneTree; ENSGT00390000005261; -.
DR HOGENOM; CLU_040186_0_2_1; -.
DR InParanoid; H3AZ19; -.
DR TreeFam; TF105960; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000013104; Expressed in chordate pharynx and 6 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR001727; GDT1-like.
DR InterPro; IPR049555; GDT1-like_CS.
DR PANTHER; PTHR12608:SF1; TRANSMEMBRANE PROTEIN 165; 1.
DR PANTHER; PTHR12608; TRANSMEMBRANE PROTEIN HTP-1 RELATED; 1.
DR Pfam; PF01169; UPF0016; 2.
DR PROSITE; PS01214; UPF0016; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 85..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 420 AA; 45893 MW; 6252D2252DE901E1 CRC64;
SPGPENKAVH DDSASKANLG FIHAFVASIS VIIVSELGDK TFFIAAIMAM RYNRLTVLAG
AMLALGLMTC LSVLFGYATT IIPRIYTYYV STALFAIFGV RMLREGLKMS PDEGQEELEE
VQAEIKKKDE EHILPHPPWG KNPSVSEISL VYTGMVCNIA DITRCGGTLC VCVQFHSGGS
PKSMEPEILN NSQLESCWCC SSKVLNKVKA GIKDFNTSLQ LAKGGKWWEK QKRSWLCFSG
TVRNNVCLAG VFEDIYCELK IKTWDNSEGE TERGEENSCQ NDCLYLTHLF AEHFGPDLNL
IQRTKLANGP GDVEIGQGAL APQKRWLHFI SPVFVQAFTL TFLAEWGDRS QLTTIVLAAR
EDPFGVAVGG TIGHCLCTGL AVIGGRMIAQ KISVRTVTII GGIVFLAFAF SALFISPEAG
//
