ID H3AZD2_LATCH Unreviewed; 311 AA.
AC H3AZD2;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Peptidase S1 domain-containing protein {ECO:0000259|PROSITE:PS50240};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000015003.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000015003.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AFYH01062935; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01062936; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3AZD2; -.
DR STRING; 7897.ENSLACP00000015003; -.
DR Ensembl; ENSLACT00000015108.1; ENSLACP00000015003.1; ENSLACG00000013204.1.
DR eggNOG; KOG3627; Eukaryota.
DR GeneTree; ENSGT00940000155138; -.
DR HOGENOM; CLU_006842_0_4_1; -.
DR InParanoid; H3AZD2; -.
DR TreeFam; TF351676; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 1.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR InterPro; IPR033116; TRYPSIN_SER.
DR PANTHER; PTHR24253:SF144; BRAIN-SPECIFIC SERINE PROTEASE 4; 1.
DR PANTHER; PTHR24253; TRANSMEMBRANE PROTEASE SERINE; 1.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
DR PROSITE; PS00135; TRYPSIN_SER; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|RuleBase:RU363034};
KW Protease {ECO:0000256|RuleBase:RU363034};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Serine protease {ECO:0000256|RuleBase:RU363034}.
FT DOMAIN 31..267
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
FT REGION 282..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 311 AA; 34188 MW; A5155D5E8362A5DB CRC64;
CVCVCVCVCV CVYIFYFSLI ECGKPVLSKR IVGGADATEG AWPWQASLHK DFRHICGAVL
ITNKWALSAA HCFEKPIYLY RYKIYFGRHL QNSYNRYEVS RGISKLLTPI SYTIALEGYD
IALIELSSSV SYTDYILPAC LPTNNTQFPE GMKCWVTGWG RDNSSDPFSV PNTLQELEVP
IIGQERCNCE YSELNITVLD GMVCTVYKGG GKGACNGDSG GPLVCKVDGA WILTGLVSWG
PENCSYPLPS VYTSVAYYQS VIQELVPEVE FVNVGPVNIN NPTVEPCTKD RTTPKPTTTP
SSTTTPNPTT T
//
