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Database: UniProt
Entry: H3B019_LATCH
LinkDB: H3B019_LATCH
Original site: H3B019_LATCH 
ID   H3B019_LATCH            Unreviewed;       447 AA.
AC   H3B019;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   11-DEC-2019, entry version 46.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSLACP00000015240};
GN   Name=LOC102359423 {ECO:0000313|Ensembl:ENSLACP00000015240};
OS   Latimeria chalumnae (Coelacanth).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Coelacanthiformes; Coelacanthidae; Latimeria.
OX   NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000015240, ECO:0000313|Proteomes:UP000008672};
RN   [1] {ECO:0000313|Ensembl:ENSLACP00000015240}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wild caught {ECO:0000313|Ensembl:ENSLACP00000015240};
RX   PubMed=9215903;
RA   Zardoya R., Meyer A.;
RT   "The complete DNA sequence of the mitochondrial genome of a 'living
RT   fossil,' the coelacanth (Latimeria chalumnae).";
RL   Genetics 146:995-1010(1997).
RN   [2] {ECO:0000313|Proteomes:UP000008672}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT   "The draft genome of Latimeria chalumnae.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSLACP00000015240}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594387}.
CC   -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594391}.
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DR   EMBL; AFYH01101358; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01101359; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01101360; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01101361; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01101362; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSLACT00000015346; ENSLACP00000015240; ENSLACG00000013416.
DR   eggNOG; KOG3806; Eukaryota.
DR   eggNOG; ENOG410Z0ZF; LUCA.
DR   GeneTree; ENSGT00940000167160; -.
DR   Proteomes; UP000008672; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00178; Ets; 1.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR   PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594397};
KW   Nucleus {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594400};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT   DOMAIN          18..103
FT                   /note="PNT"
FT                   /evidence="ECO:0000259|PROSITE:PS51433"
FT   DOMAIN          341..421
FT                   /note="ETS"
FT                   /evidence="ECO:0000259|PROSITE:PS50061"
SQ   SEQUENCE   447 AA;  51430 MW;  7C38C527E5A0E453 CRC64;
     MPLLTPGSKA VVSQALETSF SSFAKEQQLF KIHRDPRQWS EREVAQWLQW ASAEFCLGNM
     NFEKFWVTGA YLCSLGKEHF LELAPDFIGD ILWEHLEWML KDCNTTLEFR NLSSPSNQLP
     SPVFLVYFPF SATLSLLLIG RTKAEMLSVS SHYIYCLCTL SRIDTFYKKS YGIEPSRCIS
     PSGYQTSHIS PDSFQTLRNI TPEEILAMKF ENDYPALTQP THNPNYSVDP TVFLLNTELF
     HVRSPPTPEF KCTTVTKVSQ YEHLYFILYQ KSWGPPSSFS DVQRVPSYEG LEEDCGVSAL
     CSNRPKGTFK DYVRDRSDLT AMGKPVIPAS VLAGYTGSGP IQLWQFLLEL LTDKTCQSFI
     SWTGDGWEFK LTDPDEVARR WGRRKNKPKM NYEKLSRGLR YYYDKNIIHK TSGKRYVYRF
     VCDLQSLLGY APEELHSMLN IKPDTED
//
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