ID H3B0N2_LATCH Unreviewed; 670 AA.
AC H3B0N2;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Bridging integrator 1 {ECO:0000313|Ensembl:ENSLACP00000015453.1};
GN Name=BIN1 {ECO:0000313|Ensembl:ENSLACP00000015453.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000015453.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000015453.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AFYH01110389; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01110390; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01110391; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01110392; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01110393; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01110394; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01110395; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01110396; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01110397; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01110398; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3B0N2; -.
DR STRING; 7897.ENSLACP00000015453; -.
DR Ensembl; ENSLACT00000015559.1; ENSLACP00000015453.1; ENSLACG00000013605.1.
DR eggNOG; KOG3771; Eukaryota.
DR GeneTree; ENSGT00950000182882; -.
DR HOGENOM; CLU_017859_4_0_1; -.
DR InParanoid; H3B0N2; -.
DR TreeFam; TF313542; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000013605; Expressed in muscle tissue and 5 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR CDD; cd12139; SH3_Bin1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR003005; Amphiphysin.
DR InterPro; IPR035471; Amphiphysin-2_SH3.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR46514; AMPHIPHYSIN; 1.
DR PANTHER; PTHR46514:SF4; MYC BOX-DEPENDENT-INTERACTING PROTEIN 1; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF07653; SH3_2; 1.
DR PRINTS; PR01251; AMPHIPHYSIN.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 2..218
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 598..670
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 220..296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 443..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 543..568
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..240
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..294
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 670 AA; 73835 MW; DE0B0A0A7A2EADD7 CRC64;
QVLQKLGKAD ETKDEHFEQC VQNFNKQLTE GSKLQKDLRN YLNSVKAMHE ASKKLSECLQ
EIYEPDWQGR EDTTAVIENS DLLWSDYHQK LVDQALLTMD TYLGQFPDIK SRIAKRGRKL
VDYDSARHHY ESLQGAKKKD ETKIAKQKEP LKKKRNIYEE INNDLQEELP SLWNSRVGFY
VNTFQSIAGL EENFHKEMTK LNQNLHEVMV KLDKDHASNA LASKGQPSDS TPVKTDKPPS
SPVNETPPTS PETKPANHMP AAESPAASPV PPIPKSPSQL RKGPPVPPPP KLTPSKDFKQ
EQIINLFDDN FVPEISVTTP SQQESRIQHW EPVQEGGSLL DLDFDPFKPD SGTVVKAPSP
ASQSIPWDLW EVTAVCMTAE TSCCGSIVHL KSVLECLDKK KKKKKKEGKV KASKILTPCG
IKEPGDSAGD SLFAVDWPSQ PSQANTAWQD QVSETHPHPT PSQSLGSIHP SHYTTLNPVS
KKMVKKITSE LQWCLSSPPP VFSIECELTE PAATTTEATA AAASAAPVST PVQAPTAASV
SAPAAATTPA STPVPEAESE TVSSQGSLPA VVAETLPVST DDAVNDPAPS DEYEMPPGFL
FKVQTQHDYV ATDTDELDLK AGDTVLVVTF ENPDEQDEGW LMGIKETDWI QHKELLKYRG
VFPENFTARV
//
