ID H3B110_LATCH Unreviewed; 479 AA.
AC H3B110;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Solute carrier family 16 member 3 {ECO:0000313|Ensembl:ENSLACP00000015581.1};
GN Name=SLC16A3 {ECO:0000313|Ensembl:ENSLACP00000015581.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000015581.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000015581.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AFYH01016895; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01016896; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005989133.1; XM_005989071.2.
DR AlphaFoldDB; H3B110; -.
DR STRING; 7897.ENSLACP00000015581; -.
DR Ensembl; ENSLACT00000015689.1; ENSLACP00000015581.1; ENSLACG00000013718.1.
DR GeneID; 102364849; -.
DR KEGG; lcm:102364849; -.
DR CTD; 9123; -.
DR eggNOG; KOG2504; Eukaryota.
DR GeneTree; ENSGT00940000158181; -.
DR HOGENOM; CLU_001265_59_1_1; -.
DR InParanoid; H3B110; -.
DR OMA; MLCWMAV; -.
DR OrthoDB; 2917104at2759; -.
DR TreeFam; TF313792; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000013718; Expressed in pectoral fin and 3 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008028; F:monocarboxylic acid transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17430; MFS_MCT3_4; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR004743; MCT.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR NCBIfam; TIGR00892; 2A0113; 1.
DR PANTHER; PTHR11360; MONOCARBOXYLATE TRANSPORTER; 1.
DR PANTHER; PTHR11360:SF27; MONOCARBOXYLATE TRANSPORTER 4; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 21..418
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 424..479
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 424..442
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..470
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 479 AA; 52029 MW; 3AF480F223823438 CRC64;
MGTVALDDDS PKVKAPDGGW GWAILIGCFI ITGFSYAFPK AVSVFFKELI KEFGVGYSDT
AWISSILLAM LYGTGPLCSI LVNRFGCRPV MMIGGLFASL GMILASFCTS IILIYLTTGV
LTGLGLALNF QPSLIMLNRY FDKRRPLANG LSAAGSPVFL CVLSPLGQIL QDKYGWRGGF
LILGGMLLNC CVCGALMRPL DPPKQKGDTK EPSKSLTEVK PKAKLLDFTV FKDCGFIIYT
VAASIMVLGL FVPPVFVVNY AKDMKVEDTK AAALLTILGF VDMFARPTCG VIAGLKWVRP
RCVYFFAFAM VFNGFTDLMG SLSHSYDGLV VFCIFFGFSY GMVGALQFEV LMAIVGTQKF
SSALGLVLLV EACAVFIGPP SAGKLLDATH KYMFVFIMAG TEVVLSSIVL TLGNLCYMQK
KPKEAPAKQE VETVESEELK QPEENQPQSG NLDSMEVEHF LKEETEKNGE VLTNPETSV
//
