ID H3B535_LATCH Unreviewed; 380 AA.
AC H3B535;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Cell adhesion molecule 4 {ECO:0000313|Ensembl:ENSLACP00000017006.1};
GN Name=CADM4 {ECO:0000313|Ensembl:ENSLACP00000017006.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000017006.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000017006.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the nectin family.
CC {ECO:0000256|ARBA:ARBA00007810}.
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DR EMBL; AFYH01089411; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01089412; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01089413; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01089414; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01089415; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01089416; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01089417; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01089418; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01089419; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01089420; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3B535; -.
DR STRING; 7897.ENSLACP00000017006; -.
DR Ensembl; ENSLACT00000017127.1; ENSLACP00000017006.1; ENSLACG00000014975.1.
DR eggNOG; ENOG502RFJZ; Eukaryota.
DR GeneTree; ENSGT00940000161223; -.
DR HOGENOM; CLU_047574_2_0_1; -.
DR InParanoid; H3B535; -.
DR OMA; CITPRCQ; -.
DR TreeFam; TF338300; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000014975; Expressed in pectoral fin.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003234; P:bulbus arteriosus formation; IEA:Ensembl.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR003585; Neurexin-like.
DR PANTHER; PTHR45889:SF3; CELL ADHESION MOLECULE 4; 1.
DR PANTHER; PTHR45889; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00294; 4.1m; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 315..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 114..151
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 216..299
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 380 AA; 41684 MW; 50D831071C2B04A0 CRC64;
LLFFWGGGGG GSDGQIVQAE NVTVVEGGTA EINCKLHNYD HSIVVIQNPS RQTLFFNGTR
ALKDERFQLV TFTQRLVKIV LNDVKVEDEG GYFCQLYTDD THHQVATLTV AVPPENPLVE
VKEQAVEGSE AELTCIVERT KPPATLRWFR DRKEIIDCGD SQGLGNFKIE AACLTVSLCA
CRQENGGLTL SLFIHPWLPS GHSASTGHLN DVLNSPTVKI QHPGGVLREG DLFILTCSVK
GNPQPAEVIW KRLNDSLPDR VEVQDGTLTI PSLNTWDNGT YICEAENEYG AASDQYVLVV
YDPGAIIEAQ TSVPYAIIGG ILAVLVFAVI CILTVMVWCS VRQKGSYLTH EASGLDEHGE
AREAFLNGSE PHKKKEEFFI
//
