ID H3B7I0_LATCH Unreviewed; 525 AA.
AC H3B7I0;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Diaphanous-related formin 3 {ECO:0000313|Ensembl:ENSLACP00000017851.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000017851.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000017851.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the formin homology family. Diaphanous
CC subfamily. {ECO:0000256|ARBA:ARBA00008214}.
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DR EMBL; AFYH01077906; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01077907; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01077908; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01077909; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01077910; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01077911; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01077912; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01077913; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01077914; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3B7I0; -.
DR STRING; 7897.ENSLACP00000017851; -.
DR Ensembl; ENSLACT00000017981.1; ENSLACP00000017851.1; ENSLACG00000015726.1.
DR eggNOG; KOG1924; Eukaryota.
DR GeneTree; ENSGT00940000157767; -.
DR InParanoid; H3B7I0; -.
DR OMA; RRSTHEC; -.
DR TreeFam; TF315383; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR Gene3D; 6.10.30.30; -; 1.
DR Gene3D; 1.10.238.150; Formin, FH3 diaphanous domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR010472; FH3_dom.
DR InterPro; IPR014768; GBD/FH3_dom.
DR InterPro; IPR010473; GTPase-bd.
DR PANTHER; PTHR45691; PROTEIN DIAPHANOUS; 1.
DR PANTHER; PTHR45691:SF9; PROTEIN DIAPHANOUS HOMOLOG 3; 1.
DR Pfam; PF06367; Drf_FH3; 1.
DR Pfam; PF06371; Drf_GBD; 1.
DR SMART; SM01139; Drf_FH3; 1.
DR SMART; SM01140; Drf_GBD; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 1..273
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT REGION 360..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 320..347
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 370..413
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 525 AA; 60123 MW; 7D1114D323696190 CRC64;
SWVESFGNEG LGLLLDTLEK LHDKKHQEKI DKKSQYKVIQ CLKAFMNNKY GLERIMGEER
SLSMLARAID PRQPNMMTDV VKLLSAICIV GEESILEKVL EAITTAGELR NIERFCPIVE
GLRNSSVQLQ VACMQLINAL VTSPDDLDFR LHIRNEFMRC GLKEILPQLK IIRNDALDIQ
LKVFDEHKEE DMIEFSHRLE DIRSELEYYV STDTNDVYNM VLNMVKDTGA EGYLLSILQH
LLLIRNDYFI RPQYFKIIEE CISQIVLHRS GTDPDFTYRK RLDVDFYHLI DVCVDKARAE
EFEHRVSELS RKFDEEFTAR QEAQAKLQKR EEKINELEAE LHAFKSQYGA TSTVSGIPLA
QSAQGSTPTS SVPLPPPPPP VPGGMPPPPP PPPPPPPPPG CGAPPPPPPP LFKGPGVSLH
LPFGLKPKKQ FKPEINMKRF NWSKIRPHEM SENCFWVMAN EDKYEDPDVL VKLEFTFSNQ
RTVFTKNVHL IKIIRICNYF LLFLLVCLKK QQHTFAYTNV SANLN
//
