ID H3B7Y4_LATCH Unreviewed; 179 AA.
AC H3B7Y4;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Protein Dr1 {ECO:0000256|ARBA:ARBA00018742};
DE AltName: Full=Down-regulator of transcription 1 {ECO:0000256|ARBA:ARBA00032651};
DE AltName: Full=Negative cofactor 2-beta {ECO:0000256|ARBA:ARBA00030451};
GN Name=LOC102353108 {ECO:0000313|Ensembl:ENSLACP00000018005.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000018005.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000018005.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the NC2 beta/DR1 family.
CC {ECO:0000256|ARBA:ARBA00009245}.
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DR EMBL; AFYH01056377; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01056378; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01056379; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3B7Y4; -.
DR STRING; 7897.ENSLACP00000018005; -.
DR Ensembl; ENSLACT00000018136.1; ENSLACP00000018005.1; ENSLACG00000015863.1.
DR eggNOG; KOG0871; Eukaryota.
DR GeneTree; ENSGT00550000075010; -.
DR HOGENOM; CLU_066247_11_1_1; -.
DR InParanoid; H3B7Y4; -.
DR OMA; YTICEEF; -.
DR TreeFam; TF317588; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000015863; Expressed in pelvic fin.
DR GO; GO:0017054; C:negative cofactor 2 complex; IEA:InterPro.
DR GO; GO:0140223; F:general transcription initiation factor activity; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR003958; CBFA_NFYB_domain.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR042225; Ncb2.
DR PANTHER; PTHR46138; PROTEIN DR1; 1.
DR PANTHER; PTHR46138:SF1; PROTEIN DR1; 1.
DR Pfam; PF00808; CBFD_NFYB_HMF; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 24..87
FT /note="Transcription factor CBF/NF-Y/archaeal histone"
FT /evidence="ECO:0000259|Pfam:PF00808"
SQ SEQUENCE 179 AA; 20123 MW; CC80DF283FE3576D CRC64;
MKLEQRDKQA KMASASANSE EELTIPRAAI NKMIKEILPS MRVANDAREL VVNCCTEFIH
LISSEANEIC HRSDKKTINP EHVMQALESL GFGSCISEVK EALKECKTAA LQRRKANSRL
ENLGIPEEEL LRQQQELFAK AKQQQAELAQ QEWLQMQQVQ LAAASKAGSS QDEEEDDDI
//
