ID H3B9U8_LATCH Unreviewed; 865 AA.
AC H3B9U8;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=ESF1 nucleolar pre-rRNA processing protein homolog {ECO:0000313|Ensembl:ENSLACP00000018669.1};
GN Name=ESF1 {ECO:0000313|Ensembl:ENSLACP00000018669.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000018669.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000018669.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the ESF1 family.
CC {ECO:0000256|ARBA:ARBA00009087}.
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DR EMBL; AFYH01061491; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01061492; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01061493; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01061494; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01061495; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01061496; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3B9U8; -.
DR Ensembl; ENSLACT00000018802.1; ENSLACP00000018669.1; ENSLACG00000016439.1.
DR GeneTree; ENSGT00390000004881; -.
DR HOGENOM; CLU_010564_2_0_1; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000016439; Expressed in post-anal tail muscle and 6 other cell types or tissues.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR InterPro; IPR039754; Esf1.
DR InterPro; IPR012580; NUC153.
DR PANTHER; PTHR12202:SF0; ESF1 HOMOLOG; 1.
DR PANTHER; PTHR12202; UNCHARACTERIZED; 1.
DR Pfam; PF08159; NUC153; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 768..796
FT /note="NUC153"
FT /evidence="ECO:0000259|Pfam:PF08159"
FT REGION 76..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 130..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 546..581
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 638..715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 796..865
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..170
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..199
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..254
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 274..295
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..561
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 566..581
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 660..676
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 677..715
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 796..834
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 835..853
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 865 AA; 100414 MW; 3B44188BC4C08C55 CRC64;
KMSKGDLASD QRFSRVMKDP RFWEMPEKER KIKIDKRFQA MFHDKKFKLK YTVDKRGRPI
NHSTTEDLKR FYDLSDSGNS DLSDFESKKV PKKDKKKKLK AKEKVSSQKE PLDLPVEDFL
KEEENSELVK SIKKADQKVS REKLENKGQL KAKKLEREGL STKVDLARDN NKKLLQGNQS
KGDDLDSVDR SEVSHKSKQK PKGVSTQSTD FTQKRKLLGK RQSVNKMKPS EKMDEALEED
EGDSESEDDS DICEGSSSAG DLSEGRSSEE EDGESGSSGE EDSEEDDEES EEESDSGPDL
ARGKGNIETS SEEEEEDDMM ELFQQESQIE HNWGEMDKDA PRGDMVTHRL AVCNMDWDRL
KARDLLALLN SFKPKGGVVF SVKIYPSEFG KERMKAEELQ GPTELRTLPE DANQDTEEER
TLREKMRDYQ FKRLKYFYAV VDCDSPETAS KIYEECDGLE FESSCSFVDL RFVPDDVTFN
DKPKDVATEV DTAAYKPKYF TSAAMGTSKV EVTWDETDHE RVTTLSRDFK KDDIFEMDFQ
AYLASSSEEE EEEEPLPAES LEVAVEEEQN QSKKSHKNAE DQISKYKELL KSIQEKEKKY
EEKDMEMKVT WVPGLKESAE KMVKKKLEGK DKLTPWKQFL EKKKQKKKQK KKPQIADAEE
GMSDEELPPD VDLDDPYFAD ELGKPELGQR KKSKSNRKEE TTPDNEDELE RQKAEMALLM
MDDEEEDRKH FHYDKIVEQQ NMSKKKRKRL LKRQELLEED QFEMNVADPR FQAMYTSHLF
NLDPSDSNFK KTTAMQRILE EKARRREQQH QEQAEAIKRT ERELGEEEKQ QQTSKKSTDP
SLSMLIKSVK SKTQQFQARK KQKVT
//
