ID H3BBG0_LATCH Unreviewed; 613 AA.
AC H3BBG0;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 2.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Kelch like family member 6 {ECO:0000313|Ensembl:ENSLACP00000019231.2};
GN Name=KLHL6 {ECO:0000313|Ensembl:ENSLACP00000019231.2};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000019231.2, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000019231.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AFYH01032323; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01032324; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01032325; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01032326; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01032327; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3BBG0; -.
DR STRING; 7897.ENSLACP00000019231; -.
DR Ensembl; ENSLACT00000019364.2; ENSLACP00000019231.2; ENSLACG00000016915.2.
DR eggNOG; KOG4441; Eukaryota.
DR GeneTree; ENSGT00940000154345; -.
DR HOGENOM; CLU_004253_14_6_1; -.
DR InParanoid; H3BBG0; -.
DR OMA; PSTNKWN; -.
DR TreeFam; TF351654; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0050853; P:B cell receptor signaling pathway; IEA:InterPro.
DR GO; GO:0002467; P:germinal center formation; IEA:InterPro.
DR CDD; cd18446; BACK_KLHL6; 1.
DR CDD; cd18236; BTB_POZ_KLHL6; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR029851; BTB_POZ_KLHL6.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR PANTHER; PTHR24412:SF428; KELCH-LIKE PROTEIN 6; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 3.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 5.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 64..131
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 613 AA; 69800 MW; 5E95AA467D6CF130 CRC64;
MGDTVEMSTD KPCPSQQLQS KDCPRQMGDM VEKSSDGKVK FDDNGLATVL QVGLENLRLE
NSLTDVVLCV DGREFSCHRV VLAAASNYFR AMFCNDLKEK NEEKIVIKGI DAESMQILLD
YTYTSKVLIT QQNVQRILEA ASLFQFLRMV DACANFLTEA LHPDNCVGIL RLADTHCLHM
LKDQVQNFII QNFMQVLSHE EFLELPVDIL CHILKNDELN VTEEEQVFET VMHWVRYQEA
ERLPLLPQLM ENVRLPLLDP WYFVETVEAD ELIRRSTEIF PLLQEARMYH LSGNEIITER
TKPRMHEFQS EVFMIIGGCT KDEKFVSEVT CLDPLRRSRL EVSKLPITEQ ETESENKKWV
EFACITFRNE VYISGGKETQ HEVWKYTASL NKWIQTEYLN TGRWRHKMAV LGGKVYAIGG
FDGIQRLNSV ETYDPFHNCW TEVAPLMANV SSFAATSYKK KLYIIGGGPN GKLATDKTQC
YDPSANKWTL KAPMPIEAKC INAVTFRDHI YVVGGAMKAL YSYSPAEDAW CLVTRLSHER
ASCGIAACNN KLFITGGRDE KNEVIATVLC WDTETLKLTE ECVLPRGVSH HGSVTVRKSY
THIRRIVPGA ISV
//
