ID H3BC52_LATCH Unreviewed; 398 AA.
AC H3BC52;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 2.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=RILP-like protein 1 {ECO:0000256|ARBA:ARBA00040816};
DE AltName: Full=Rab-interacting lysosomal-like protein 1 {ECO:0000256|ARBA:ARBA00042424};
GN Name=RILPL1 {ECO:0000313|Ensembl:ENSLACP00000019473.2};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000019473.2, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000019473.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the RILPL family.
CC {ECO:0000256|ARBA:ARBA00038318}.
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DR EMBL; AFYH01016358; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01016359; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005989001.1; XM_005988939.1.
DR AlphaFoldDB; H3BC52; -.
DR Ensembl; ENSLACT00000019610.2; ENSLACP00000019473.2; ENSLACG00000017123.2.
DR GeneID; 102353336; -.
DR CTD; 353116; -.
DR GeneTree; ENSGT00940000157897; -.
DR HOGENOM; CLU_044133_3_0_1; -.
DR OrthoDB; 5400045at2759; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000017123; Expressed in post-anal tail muscle and 6 other cell types or tissues.
DR GO; GO:0005929; C:cilium; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd14445; RILP-like; 1.
DR Gene3D; 1.20.58.1770; -; 1.
DR Gene3D; 6.10.230.10; -; 1.
DR InterPro; IPR019143; JNK/Rab-associated_protein-1_N.
DR InterPro; IPR034743; RH1.
DR InterPro; IPR034744; RH2.
DR InterPro; IPR021563; RILP_dimer.
DR PANTHER; PTHR21502:SF6; RILP-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR21502; ZINC FINGER PROTEIN DZIP1; 1.
DR Pfam; PF09744; Jnk-SapK_ap_N; 1.
DR Pfam; PF11461; RILP; 1.
DR SUPFAM; SSF161256; RILP dimerisation region; 1.
DR PROSITE; PS51776; RH1; 1.
DR PROSITE; PS51777; RH2; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 3..90
FT /note="RH1"
FT /evidence="ECO:0000259|PROSITE:PS51776"
FT DOMAIN 284..351
FT /note="RH2"
FT /evidence="ECO:0000259|PROSITE:PS51777"
FT REGION 244..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 374..398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 398 AA; 46512 MW; 27748199126BB8C4 CRC64;
MDAGVSALEK KVADLTVMDV YDIAAVVGQE FERIIDQHGC EAIARLMPKV VRVLEILEVL
VSRNNINPEM EELRLELDRL RLERMDRLEK ERKHQKELEL VEDVWRGEAQ DLLTQIAQLQ
EENKQLMTNL SQKDITLSEE ELQRQEGMSE RERQVMKKLK EVVDKQRDEI RAKDRELGLR
NDDIEALQQQ QNRLMKINHD LRHKITVVEA QGKTLIEQKV ELEAYLQTKE QEMARMKAEL
GKMREKVQGQ QSQNGEEKQA EPMDDGGDLY ESEKMVVDLK DPNRPRFTLQ ELRDVLHERN
ELKAKVFLLQ EELAYYKSEE IEEETGPPQP SPQPIIHLKP AIQQESGIKR LFSFFSRDKK
RGYSTQKNVR FQEPFGTWAA PDGDEGYTEQ GQEALQHM
//
