ID H3BFF8_LATCH Unreviewed; 261 AA.
AC H3BFF8;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};
GN Name=ZGC:113223 {ECO:0000313|Ensembl:ENSLACP00000020629.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000020629.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000020629.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU361218}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}.
CC -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC {ECO:0000256|ARBA:ARBA00006840, ECO:0000256|RuleBase:RU361218}.
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DR EMBL; AFYH01022117; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3BFF8; -.
DR Ensembl; ENSLACT00000020769.1; ENSLACP00000020629.1; ENSLACG00000018126.1.
DR GeneTree; ENSGT00940000165051; -.
DR HOGENOM; CLU_055524_0_0_1; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000018126; Expressed in pelvic fin and 1 other cell type or tissue.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd03158; penumbra_like_LEL; 1.
DR Gene3D; 1.10.1450.10; Tetraspanin; 1.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR000301; Tetraspanin_animals.
DR InterPro; IPR008952; Tetraspanin_EC2_sf.
DR PANTHER; PTHR19282; TETRASPANIN; 1.
DR PANTHER; PTHR19282:SF168; TETRASPANIN; 1.
DR Pfam; PF00335; Tetraspanin; 1.
DR PIRSF; PIRSF002419; Tetraspanin; 1.
DR PRINTS; PR00259; TMFOUR.
DR SUPFAM; SSF48652; Tetraspanin; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361218};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Transmembrane {ECO:0000256|RuleBase:RU361218};
KW Transmembrane helix {ECO:0000256|RuleBase:RU361218}.
FT TRANSMEM 7..31
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT TRANSMEM 51..72
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT TRANSMEM 79..103
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT TRANSMEM 221..246
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
SQ SEQUENCE 261 AA; 29379 MW; 2709777CB6C4C60A CRC64;
RMAISPVVKY ILFASCYVFW VASGLMIAVG IYAKVAKEAE AVDSLTADPA LILIVVGLLM
FGITFVGCFG ALRLSKCMLM IFAWTLLIIL ILQVVAAVLG FLFSSMVLEK AADLMEKAIS
NYRDDLDLQN LIDFIQKKLK CCGVNGYMDW SHNIYFNCKD RNPSLERCAV PFSCCIQKRE
EFVLNTMCGY EMQQQPEWKA EQGIYVKGCL DQITTWGQQN LLLIGGISLG LFFLEIIMIT
LAFILIQQIQ FLNLRRTLSA D
//
