ID H3BHE9_LATCH Unreviewed; 495 AA.
AC H3BHE9;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Phospholipid transfer protein {ECO:0000313|Ensembl:ENSLACP00000021320.1};
GN Name=PLTP {ECO:0000313|Ensembl:ENSLACP00000021320.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000021320.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000021320.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
CC {ECO:0000256|ARBA:ARBA00007292}.
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DR EMBL; AFYH01003906; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01003907; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01003908; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01003909; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3BHE9; -.
DR STRING; 7897.ENSLACP00000021320; -.
DR Ensembl; ENSLACT00000021461.1; ENSLACP00000021320.1; ENSLACG00000018736.1.
DR eggNOG; KOG4160; Eukaryota.
DR GeneTree; ENSGT01100000263545; -.
DR HOGENOM; CLU_028970_2_0_1; -.
DR InParanoid; H3BHE9; -.
DR OMA; GMFAYYS; -.
DR TreeFam; TF315617; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000018736; Expressed in pelvic fin and 6 other cell types or tissues.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR CDD; cd00025; BPI1; 1.
DR InterPro; IPR017943; Bactericidal_perm-incr_a/b_dom.
DR InterPro; IPR030675; BPI/LBP.
DR InterPro; IPR032942; BPI/LBP/Plunc.
DR InterPro; IPR001124; Lipid-bd_serum_glycop_C.
DR InterPro; IPR017954; Lipid-bd_serum_glycop_CS.
DR InterPro; IPR017942; Lipid-bd_serum_glycop_N.
DR PANTHER; PTHR10504; BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED; 1.
DR PANTHER; PTHR10504:SF16; PHOSPHOLIPID TRANSFER PROTEIN; 1.
DR Pfam; PF01273; LBP_BPI_CETP; 1.
DR Pfam; PF02886; LBP_BPI_CETP_C; 1.
DR PIRSF; PIRSF002417; Lipid_binding_protein; 1.
DR SMART; SM00328; BPI1; 1.
DR SMART; SM00329; BPI2; 1.
DR SUPFAM; SSF55394; Bactericidal permeability-increasing protein, BPI; 2.
DR PROSITE; PS00400; LBP_BPI_CETP; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR002417-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..495
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012903916"
FT DOMAIN 23..241
FT /note="Lipid-binding serum glycoprotein N-terminal"
FT /evidence="ECO:0000259|SMART:SM00328"
FT DOMAIN 256..462
FT /note="Lipid-binding serum glycoprotein C-terminal"
FT /evidence="ECO:0000259|SMART:SM00329"
FT DISULFID 144..183
FT /evidence="ECO:0000256|PIRSR:PIRSR002417-50"
SQ SEQUENCE 495 AA; 54972 MW; 1D15119D8AB41943 CRC64;
FLIVILSCAA SMAAATSPAC KIRVTSRGLD LVRDEGLKFL EQELENITIP DLSGKEGGFH
YTVKEVKITD LYLPAPDLWF QPQKSLGFHI ENASITLNFQ RKILYWFFRD VGSINASAEG
VNMKTTLEMS KDAFGRLKIS NVTCNASISK MHAKFSGTLG RVYDFIATFI TTGMRFLLNR
QICPALNHAS LVLLNSFLDT VPVRSEVDNY VGIDYSLLSD PVVSANSLDM DFKGMFYDLS
NENHTLTNYA VTPVIKQNER MVYVAFSEYF FDSALYSYYK AGAYQMEISD EKMPKDLEVF
LRTTYLGTIM LLMKDPSAVD APMKLEIQVS TPPRCTIKPS GTTVSVNAIL KVILAPEGRP
PIQLSSMTME TKMNGRISLN GKKLLITLSL KRFKIYSNQS ALESLALIPL QSPLKTLLQI
AVMPIINVIE RTKKGVQIPL PEGMDFVKDD IENHAGFIIV AADLHFSKGL GEIINKYRSA
TESKPAANPK SSTAV
//
