ID H3BHF3_LATCH Unreviewed; 273 AA.
AC H3BHF3;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Growth differentiation factor 11 {ECO:0000313|Ensembl:ENSLACP00000021324.1};
GN Name=LOC102358538 {ECO:0000313|Ensembl:ENSLACP00000021324.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000021324.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000021324.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656}.
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DR EMBL; AFYH01001597; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01001598; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01001599; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01001600; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01001601; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01001602; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01001603; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01001604; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01001605; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01001606; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3BHF3; -.
DR Ensembl; ENSLACT00000021465.1; ENSLACP00000021324.1; ENSLACG00000018739.2.
DR GeneTree; ENSGT00940000166043; -.
DR HOGENOM; CLU_097767_0_0_1; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000018739; Expressed in pharyngeal gill and 3 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.970; -; 1.
DR InterPro; IPR001111; TGF-b_propeptide.
DR InterPro; IPR015615; TGF-beta-rel.
DR PANTHER; PTHR11848:SF166; GROWTH_DIFFERENTIATION FACTOR 11; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00688; TGFb_propeptide; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..273
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003580133"
FT DOMAIN 43..268
FT /note="TGF-beta propeptide"
FT /evidence="ECO:0000259|Pfam:PF00688"
SQ SEQUENCE 273 AA; 31255 MW; 3220C3E4875A8226 CRC64;
MPRSHFFLCL MLISLEFSGS DEPSLEQGPS EGGSSLVVEG EQGCPACMWR EHSKVLRLET
IKSQILSKLR LKQAPNISRE VVNQLLPKAP PLQQLLDQHD FQGDSTLPEE FLEEDEYHAT
TETVITMASE RNCFFFFRRL CHCEHVSTPD PSVQIDGKPR CCFFKFSPKI MFTKVVKAQL
WVYLRPIQQT STVYLQILRL KPVTEEGSRH IRIRSLKIDL NSRSGHWQSI DFKHVLQNWF
KQPHTNWGIE INAFDTNGND LAVTSLGPGE EGL
//
