ID H3BHG9_LATCH Unreviewed; 611 AA.
AC H3BHG9;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Solute carrier family 13 member 5 {ECO:0000313|Ensembl:ENSLACP00000021340.1};
GN Name=SLC13A5 {ECO:0000313|Ensembl:ENSLACP00000021340.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000021340.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000021340.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family.
CC NADC subfamily. {ECO:0000256|ARBA:ARBA00006772}.
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DR EMBL; AFYH01008641; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01008642; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3BHG9; -.
DR STRING; 7897.ENSLACP00000021340; -.
DR Ensembl; ENSLACT00000021481.1; ENSLACP00000021340.1; ENSLACG00000018751.1.
DR eggNOG; KOG1281; Eukaryota.
DR GeneTree; ENSGT01030000234550; -.
DR HOGENOM; CLU_005170_9_1_1; -.
DR InParanoid; H3BHG9; -.
DR OMA; IWWMTEA; -.
DR TreeFam; TF312913; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015370; F:solute:sodium symporter activity; IEA:UniProt.
DR CDD; cd01115; SLC13_permease; 1.
DR InterPro; IPR031312; Na/sul_symport_CS.
DR InterPro; IPR001898; SLC13A/DASS.
DR PANTHER; PTHR10283; SOLUTE CARRIER FAMILY 13 MEMBER; 1.
DR PANTHER; PTHR10283:SF109; SOLUTE CARRIER FAMILY 13 MEMBER 5; 1.
DR Pfam; PF00939; Na_sulph_symp; 1.
DR PROSITE; PS01271; NA_SULFATE; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00023201};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Sodium {ECO:0000256|ARBA:ARBA00023201};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 16..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 445..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 482..515
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 527..547
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 567..586
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 168..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 611 AA; 67336 MW; CD1179113F719B2A CRC64;
LPCNKMVSTI KALWQFKNFI IILLTPLLLL PLPLVLQTKE AKAAYVIILM AIYWCTEVIP
LAVTALLPAI LFPMFGILES GKVCMQYLKD TNMLFVGGLM VAIAVEHWNL HKRIALRVLL
MVGVKPALLM LGFMGVTAFL SMWISNTATT AMMIPIVQAV LQQLNNTEKE KSQAENENGQ
INSGAETEEK NTLSMISVQG KKGNGNVPAE PQTHTDSFDK KNMCKGLTLC ICYAASIGGT
ATLTGTGPNL VLKGQISQLF PQNGDVVNFA SWFGFAFPNM ILMLTLAWLW LQFVFMGLNF
KKTWGCGGQK SEKEIAAYNV IKEEYQKLGP MTFAEVNVLI LFTLLVVLWF TREPGFVPGW
ATYLFNSDQE FVTDATVAVF IAILLFIVPS KKPTFKCWNR SSYDTKTNVT VKLQTVQSLN
SILSRIVKGD ILTPLLNWKV VQKNMPWNII LLLGGGFAVA KGCEASGLSK WLGTQMIPLQ
SIPPWAIVIV LTLLLAIFTE CTSNVATATI FLPILASMSQ SIEMNPLYVM IPCTLSTSFA
FMLPVATPPN AIVFSYGQLR VSDMAKTGII MNIIGLLCVT LAINSWGRAM FNLDTFPTWA
NATARNVTKM P
//
