ID H3BHU3_LATCH Unreviewed; 319 AA.
AC H3BHU3;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Activating transcription factor 1 {ECO:0000313|Ensembl:ENSLACP00000021464.1};
GN Name=ATF1 {ECO:0000313|Ensembl:ENSLACP00000021464.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000021464.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000021464.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AFYH01001701; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01001702; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_014353996.1; XM_014498510.1.
DR RefSeq; XP_014354032.1; XM_014498546.1.
DR RefSeq; XP_014354058.1; XM_014498572.1.
DR AlphaFoldDB; H3BHU3; -.
DR STRING; 7897.ENSLACP00000021464; -.
DR Ensembl; ENSLACT00000021605.1; ENSLACP00000021464.1; ENSLACG00000018861.1.
DR GeneID; 102361374; -.
DR CTD; 466; -.
DR eggNOG; KOG3584; Eukaryota.
DR GeneTree; ENSGT00940000158200; -.
DR HOGENOM; CLU_042675_0_1_1; -.
DR InParanoid; H3BHU3; -.
DR OMA; THISHIA; -.
DR OrthoDB; 3137625at2759; -.
DR TreeFam; TF106464; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000018861; Expressed in muscle tissue and 6 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR CDD; cd14690; bZIP_CREB1; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR InterPro; IPR003102; CREB1-like_pKID.
DR InterPro; IPR001630; Leuzip_CREB.
DR PANTHER; PTHR45879; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B; 1.
DR PANTHER; PTHR45879:SF2; CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-1; 1.
DR Pfam; PF00170; bZIP_1; 1.
DR Pfam; PF02173; pKID; 1.
DR PRINTS; PR00041; LEUZIPPRCREB.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR PROSITE; PS50217; BZIP; 1.
DR PROSITE; PS00036; BZIP_BASIC; 1.
DR PROSITE; PS50953; KID; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 77..136
FT /note="KID"
FT /evidence="ECO:0000259|PROSITE:PS50953"
FT DOMAIN 261..312
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 77..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 279..313
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 77..98
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 319 AA; 34341 MW; F40F3BCFB6492D9E CRC64;
MEEVQASSNG TETAAQSHSV SAVTLQPSQI SQLSQQMSLG GSSPLTVVQL PGSQIQGVIQ
TAQPSSVIQS PQIQTVQVSS LSESDDSQES SDSMGSSQKA REILARRPSY RKIFNDLSSE
DTAARPDRRG NEEAIAASAV TTMSVPTSIY QTSTGQYIAI APNGAIQLAS TVTEGVQGLQ
TLTMTNAGGN QQGATILQYA QTADGQQILV PSNQVVLHTA SGDMQAYQIR TNPTTTALPQ
TVVMTSPVSL SAQSTKTDDP QLKREIRLMK NREAARECRR KKKEYVKCLE NRVAVLENQN
KTLIEELKTL KDLYCHKAV
//
