ID H3BJR5_MOUSE Unreviewed; 664 AA.
AC H3BJR5;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Vomeronasal 2, receptor 96 {ECO:0000313|Ensembl:ENSMUSP00000131564.2};
GN Name=Vmn2r96 {ECO:0000313|Ensembl:ENSMUSP00000131564.2,
GN ECO:0000313|MGI:MGI:3644514};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000131564.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000131564.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000131564.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000131564.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000131564.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; NP_001098017.1; NM_001104547.1.
DR AlphaFoldDB; H3BJR5; -.
DR SMR; H3BJR5; -.
DR STRING; 10090.ENSMUSP00000131564; -.
DR PaxDb; 10090-ENSMUSP00000131564; -.
DR Ensembl; ENSMUST00000165692.8; ENSMUSP00000131564.2; ENSMUSG00000091679.10.
DR AGR; MGI:3644514; -.
DR MGI; MGI:3644514; Vmn2r96.
DR VEuPathDB; HostDB:ENSMUSG00000091679; -.
DR GeneTree; ENSGT00950000183069; -.
DR OrthoDB; 4775989at2759; -.
DR TreeFam; TF340115; -.
DR ChiTaRS; Vmn2r96; mouse.
DR Proteomes; UP000000589; Chromosome 17.
DR Bgee; ENSMUSG00000091679; Expressed in granulocyte and 5 other cell types or tissues.
DR ExpressionAtlas; H3BJR5; baseline and differential.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IBA:GO_Central.
DR CDD; cd15283; 7tmC_V2R_pheromone; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR InterPro; IPR004073; GPCR_3_vmron_rcpt_2.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24061:SF492; VOMERONASAL 2, RECEPTOR 100-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01535; VOMERONASL2R.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 391..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 461..485
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 505..523
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 555..573
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 585..605
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 611..632
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 391..655
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 664 AA; 75867 MW; 3290A772B71739C5 CRC64;
MAPKDTSLSL AIVSLMVHFR WTWVGLILPN DHKGNKILSD FREEMERNGI CLAFVKMTPE
TWTSYVAKFW ENMDETNVTI IYGEIDSLEG IMRNIEQRLL TWNVWIMNIE HHVIDRADYF
MLDSFHGSLI FKHNYRENIE FTKFIQTVNP NKYPEDIYLP KLWYLFFKCS FSDTNCHVLE
NCQTNATLDI FPRHIFDMVM NAESTIIYNG VYAVAYSLHE MRLQLLQMQP YENHHGMVFF
PWQLNTFLKN IVVKDKRSLD WRQTIDAEYD ILNIWNLPKG LGLKVKIGSF SANAPLGQQL
SLSEQMIQWP AMFSEIPQSV CSESCGPGFR KVTLEGKAIC CYKCTPCADN EISNETDVDT
CVKCPERHYA NAEKSNCFQK SVSFLAYEDT LGMALASIAL CLSVLTAFVI GIFVKHRDTP
IVKANNRALS YILLITLTFC FLCSLNFIGK PTTVSCILQQ TTFAVAFTMA LATVLAKAIT
VVLAFKVSFP GRMIRWLMIS RGPNYIIPIC TLIQLLICGI WMATSPPFID QDAHTEYGHI
IILCNKGSSV AFHSVLGYLC FMALGSYAMA FLSRNLPDTF NESKFLSFSM LVFFCVWVTF
LPVYHSTKGK VMVAMEVFSI LASSTALLAF IFGPKCYIIL LRPDKNSFNY IRKKTPSRKN
FPKI
//
