ID H3BPT7_HUMAN Unreviewed; 280 AA.
AC H3BPT7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Zinc finger protein 276 {ECO:0000313|Ensembl:ENSP00000455466.1};
GN Name=ZNF276 {ECO:0000313|Ensembl:ENSP00000455466.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000455466.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000455466.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15616553; DOI=10.1038/nature03187;
RA Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G.,
RA Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E.,
RA Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J., Buckingham J.M.,
RA Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C.,
RA Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M.,
RA Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M.,
RA Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D.,
RA Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L.,
RA Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E.,
RA Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H.,
RA Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y.,
RA Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S.,
RA Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A.,
RA Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M.,
RA Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H.,
RA Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A.,
RA Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J.,
RA DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J.,
RA Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M.,
RA Myers R.M., Rubin E.M., Pennacchio L.A.;
RT "The sequence and analysis of duplication-rich human chromosome 16.";
RL Nature 432:988-994(2004).
RN [2] {ECO:0000313|Ensembl:ENSP00000455466.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC005360; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC010538; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3BPT7; -.
DR SMR; H3BPT7; -.
DR MassIVE; H3BPT7; -.
DR MaxQB; H3BPT7; -.
DR PeptideAtlas; H3BPT7; -.
DR ProteomicsDB; 41590; -.
DR Ensembl; ENST00000562530.5; ENSP00000455466.1; ENSG00000158805.12.
DR UCSC; uc059yrk.1; human.
DR HGNC; HGNC:23330; ZNF276.
DR VEuPathDB; HostDB:ENSG00000158805; -.
DR GeneTree; ENSGT00940000158841; -.
DR ChiTaRS; ZNF276; human.
DR Proteomes; UP000005640; Chromosome 16.
DR Bgee; ENSG00000158805; Expressed in granulocyte and 154 other cell types or tissues.
DR ExpressionAtlas; H3BPT7; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR InterPro; IPR012934; Znf_AD.
DR Pfam; PF07776; zf-AD; 1.
DR PROSITE; PS51915; ZAD; 1.
PE 1: Evidence at protein level;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU01263};
KW Proteomics identification {ECO:0007829|EPD:H3BPT7,
KW ECO:0007829|MaxQB:H3BPT7};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU01263};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU01263}.
FT DOMAIN 2..88
FT /note="ZAD"
FT /evidence="ECO:0000259|PROSITE:PS51915"
FT REGION 193..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..236
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 4
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 7
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 61
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 64
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
SQ SEQUENCE 280 AA; 30155 MW; 737A136621777A11 CRC64;
MGHCRLCHGK FSSRSLRSIS ERAPGASMER PSAEERVLVR DFQRLLGVAV RQDPTLSPFV
CKSCHAQFYQ CHSLLKSFLQ RVNASPAGRR KPCAKVGAQP PTGAEEGACL VDLITSSPQC
LHGLVGWVHG HAASCGALPH LQRTLSSEYC GVIQVVWGCD QGHDYTMDTS SSCKAFLLDS
ALAVKWPWDK ETAPRLPQHR GWNPGDAPQT SQGRGTGTPV GAETKTLPST DVAQPPSDSD
AVGPRSGFPP QPSLPLCRAP GQLGEKQLPS STSDDRRRLE
//
