ID H3BX42_TETNG Unreviewed; 1109 AA.
AC H3BX42;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Myosin IF {ECO:0000313|Ensembl:ENSTNIP00000000555.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000000555.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000000555.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR AlphaFoldDB; H3BX42; -.
DR STRING; 99883.ENSTNIP00000000555; -.
DR Ensembl; ENSTNIT00000004147.1; ENSTNIP00000000555.1; ENSTNIG00000010162.1.
DR GeneTree; ENSGT00940000158870; -.
DR InParanoid; H3BX42; -.
DR OMA; GCHEHFN; -.
DR TreeFam; TF312960; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd01378; MYSc_Myo1; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR010926; Myosin_TH1.
DR InterPro; IPR036072; MYSc_Myo1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF663; UNCONVENTIONAL MYOSIN-IF; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF06017; Myosin_TH1; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS51757; TH1; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Membrane {ECO:0000256|SAM:Phobius};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 45..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..695
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 733..922
FT /note="TH1"
FT /evidence="ECO:0000259|PROSITE:PS51757"
FT DOMAIN 1050..1109
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 572..594
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 921..954
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1026..1052
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 921..935
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 114..121
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1109 AA; 127034 MW; 3DEB2E9931B69651 CRC64;
ISSKAKYHWQ SQNVKQSGVD DMVLLSKITE DAIVENLKKR YMDDYIFVSF LTYIGPVLIS
VNPFKQMPYF TEREIELYQG AAQYENPPHI YALTDNMYRN MMIDGENQCV IISGESGAGK
TVAAKYIMGY ISKVSGGGAK VQQHVKDIIL QSNPLLEAFG NAKTVRNNNS SRFGKYFEIQ
FSRGGEPDGG KISNFLLEKS RVVSQNENER NFHIYYQLIE GTNAQQKEGL GIMTPDYYNY
LNQSGTYKVD GTNDSKDFQE TMEAMQVIGI PGDIQMQVLN IVAGILHLGN ISFVEAGNYA
KVESTDLLAF PAYLLGINPD RLQDKLTSRK MDSKWGGKSE SITVTLNQEQ ANYTRDALAK
ALYARLFDYL VEAINKAIQK PHEEFSIGVL DIYGFEIFQR NGFEQFCINF VNEKLQQIFI
ELTLKAEQEE YVQEGIKWTP IQYFNNKIVC DLIENKVNPT GIMSVLDDVC ATMHAKGEGA
DGTLLQKLQA TVGTHEHFNS WNSGFVIHHY AGKVSYDING FCERNRDVLF PDLIELMQSS
EHRFICSLFP ENLNTEKKGR PTTASSKIKK QANDLVNTLM KCTPHYIRCI KPNETKRPKD
WEESRVKHQV EYLGLRENIR VRRAGFAYRR VFTKFLMRYA ILTAETWPSW RGPEQQGVLH
LLRSVNMETD QYQMGRTKIF VKNPESLFLL EEMRERKFDT FARIIQKCWR RFIARKKYEQ
MREEASDILH NAKERRKNSI NRNFVGDYLG LEHRPELRQF LAKRERIDFA ASIDKLDRRF
KSIKRDLILT PKAIYLIGRE KVKKGPEKGQ IKEVLKRKLE FGSISSVSLS TRQDDFFVLH
ESQYDSLLES TFKTEFLSLL SKRYEDVTKR QLTISFSDRI EFRVKKEGWG GGGSRLVVFQ
RGQGDLALLK PAGKTLTITI GDGLPKSSKP SRKNATQHHA GGGRNVKTTN PNPNPHHYLT
FNDVQSRYQM VVAPAHQPSE VMYSAPHRPP STILPKLNSQ QRAPRAPVQN QYNQTNMDFL
NVPDQGMSGK QRKRSITQRP LPAPKPQPRP AAPRCRALYQ YTGQDTDEIS FDVNDVIDLL
NSSADPSGWW TGRFRGREGL FPGNYVEKI
//
