ID H3BXP3_TETNG Unreviewed; 1065 AA.
AC H3BXP3;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Glutamate receptor interacting protein 2b {ECO:0000313|Ensembl:ENSTNIP00000000756.1};
GN Name=GRIP2 {ECO:0000313|Ensembl:ENSTNIP00000000756.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000000756.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000000756.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H3BXP3; -.
DR Ensembl; ENSTNIT00000002813.1; ENSTNIP00000000756.1; ENSTNIG00000005990.1.
DR GeneTree; ENSGT00940000155615; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR CDD; cd00992; PDZ_signaling; 7.
DR Gene3D; 2.30.42.10; -; 7.
DR InterPro; IPR043545; GRIP1/2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR46227:SF4; GLUTAMATE RECEPTOR-INTERACTING PROTEIN 2; 1.
DR PANTHER; PTHR46227; GLUTAMATE RECEPTOR-INTERACTING PROTEIN GRIP; 1.
DR Pfam; PF00595; PDZ; 7.
DR SMART; SM00228; PDZ; 7.
DR SUPFAM; SSF50156; PDZ domain-like; 7.
DR PROSITE; PS50106; PDZ; 7.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007303}.
FT DOMAIN 37..125
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 140..229
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 243..327
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 464..539
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 565..648
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 664..747
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 979..1061
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 330..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 385..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 752..781
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 833..867
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 917..951
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 333..347
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..422
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 925..940
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1065 AA; 115264 MW; 896376C68AE0400A CRC64;
LCLDDGPYGK TKDLSGPEQT MSSRRHSIPE ALRGVTMVEL VKKEGSTLGL TISGGTDKDG
KPRVSNLRPG GLAAALLLCR SDQLNVGDYI KSVNGINLTK LRHEEIISLL KNVGERVLLE
VEYELPPTAP NSTSGLISKT IDICLHKEGS SFGFVVRGGA HEDWHKSRPL VVTYVRPGGP
ADSREGTLRP GDRLLSVDGV PLQSTNHSDA LTLLAQCGQE ALFQIEYDVT IMDTVANASG
PLLVEIIKSP GATLGITLTS ANHRNKQVIV IDRIKSGSVV DRCGALHTGD HLLSIDGTST
EHCSVLEATQ LLASTTELVK LEILPSHQTR LTGKQHDAVK VQKSDHPHSW DPCSALNKSW
TASNNNTINS VDYCKCRTAD TPADLSPDPL ENSEESEHFS PGSTTTSGAS GQNSSTLPRP
AVPMSPRNSL LKRRQRKKDH KSSLSLASSS VGPGGQVVHV ETSEVVLNGD PLNGFGVQLQ
GGIFATETLS APPLIRFIEP DSSAERCGLL QVGDRLLSIN GIPTEDGTLE EANQLLRDAA
LTNKVTLEIE FDVAESVVPS SGTFHVKLPK KRGVELGLTI SASKKPGEPL IISDIKKGSM
AHRTGTLEPG DKLLAIDNIR LENCSREEAE QILQQCEELV KLKIRKDEDN SEMSRRRQAA
SFYTVELKRY GGPLGITISG TEEPFDPITI SGLTKRGLAE RRTGAIHVGD RILAINSVSL
KGKPLSEAIH LLQMAGETVT LKIKKQLDNL EEKKSSELED ATENELSEPE EDELTDSQQT
NKLSELYSTT IPSVDSAMDS WDGSGLDAGY GSQGTYSHQA AGIALHPHEW RSAKQPLSTT
PPPGRQKNYP FSDGGFSEDD WDRPAGRFLG QQADGILLDP EDSFWCQALE DLETCGQSEL
LREIEASIMT GTAISLGIRS PAPGAPLQPR GPPAPRSTPA PHEAKPKASL RVSERTWESR
RIKEEMQGIV SPTPLELHKV TVIKDPEIDD FGFSVSDGFL EKGVYVNMIR ADGPADRAGL
KPFDRILQVN HVRTRDFDCC LAVPLITEAG DRLELVISRN PLASE
//
