ID H3C500_TETNG Unreviewed; 726 AA.
AC H3C500;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Upstream binding transcription factor {ECO:0000313|Ensembl:ENSTNIP00000003319.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000003319.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000003319.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H3C500; -.
DR STRING; 99883.ENSTNIP00000003319; -.
DR Ensembl; ENSTNIT00000001453.1; ENSTNIP00000003319.1; ENSTNIG00000004271.1.
DR GeneTree; ENSGT00940000166349; -.
DR InParanoid; H3C500; -.
DR OMA; RTAYKEY; -.
DR TreeFam; TF328989; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd21998; HMG-box_UBF1_rpt1-like; 1.
DR CDD; cd21999; HMG-box_UBF1_rpt2; 1.
DR CDD; cd22000; HMG-box_UBF1_rpt3; 1.
DR CDD; cd22001; HMG-box_UBF1_rpt4; 1.
DR CDD; cd22002; HMG-box_UBF1_rpt5; 1.
DR CDD; cd22003; HMG-box_UBF1_rpt6-like; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 6.
DR InterPro; IPR029215; HMG_box_5.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR46318; UPSTREAM BINDING TRANSCRIPTION FACTOR; 1.
DR Pfam; PF00505; HMG_box; 3.
DR Pfam; PF09011; HMG_box_2; 1.
DR Pfam; PF14887; HMG_box_5; 1.
DR SMART; SM00398; HMG; 6.
DR SUPFAM; SSF47095; HMG-box; 6.
DR PROSITE; PS50118; HMG_BOX_2; 6.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 104..172
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 193..261
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 295..359
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 403..471
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 475..542
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 562..628
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 104..172
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 193..261
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 295..359
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 403..471
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 475..542
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 562..628
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 283..304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 373..407
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 550..571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 631..726
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 677..692
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 693..712
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 726 AA; 85268 MW; 7B7A2CCCF7369396 CRC64;
MNGEMETSAQ DQVWVQDDLL KLLEAMKVAL PQKDLTKYKT SESHLDWQKV AFNSYTAEMC
KQKWQEVSKE IRKFRTLTEL IVDAQDYIKN PYKGKKIKKH PDFPKKPLTP YFRFFMEKRA
KYAKLHPEMS NLDLTKILSK KYRELPEKKK KKYVDDFLRD KEMFVQSMDK FSKYREEHPD
LVESMAKKGS NVPEKPKTPQ QLWYNHEKKA FLKTHPEATT KDIKDNLGKQ WTQLSDKKRL
KWITKSLEQR KLYEEVMREY IQQHPELNMT QDDIVKSTLT KAERHLKDKS DGRPDKPPPN
GYSMFCAELM SNMKDVPSTE RMVMCSQRWK LLKQGEKDAY QKRCEQRKKE YEIEMNRFLS
TLSEQEQQRV LSEEKIGYKK GTGASSPASK KKNSKTKASP EKPKRPISAM FIFSEEKRPK
LQQERPDLSD SELTRLLARM WNELPDKKKE KYKRLEIVLK AESVKKEKED RSRLPDPPKT
AQEIWQQSVI GDYMARFKSD RSKAQKAMEA TWSNMEKKEK IMWIKKAAED QKRYERELYE
MRSPAAAAIA SGKKMKFEGE PKKPPSNGYQ KFSQEMLSNG ELNHLPMKER MTEIGSRWQR
LPLKDKDRYK KIAEEKQRQY KVQLEQWLAS LSSQERNTYK EYNSQKRKSA AKPGGPKAKS
KKSVSTDAAL QVSREEEQQD TEEEEEAEKA SSEADSSEEG GEDKENKSED SSSESNSQES
SDSDSD
//
