ID   H3C9T3_TETNG            Unreviewed;      1072 AA.
AC   H3C9T3;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=Family with sequence similarity 135 member A {ECO:0000313|Ensembl:ENSTNIP00000005005.1};
OS   Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS   nigroviridis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX   NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000005005.1, ECO:0000313|Proteomes:UP000007303};
RN   [1] {ECO:0000313|Proteomes:UP000007303}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15496914; DOI=10.1038/nature03025;
RA   Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA   Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA   Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA   Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA   Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA   Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA   Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA   McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA   Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA   Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA   Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT   "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT   early vertebrate proto-karyotype.";
RL   Nature 431:946-957(2004).
RN   [2] {ECO:0000313|Ensembl:ENSTNIP00000005005.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the FAM135 family.
CC       {ECO:0000256|ARBA:ARBA00007949}.
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DR   AlphaFoldDB; H3C9T3; -.
DR   Ensembl; ENSTNIT00000005151.1; ENSTNIP00000005005.1; ENSTNIG00000016584.1.
DR   GeneTree; ENSGT00940000157565; -.
DR   HOGENOM; CLU_003176_0_0_1; -.
DR   Proteomes; UP000007303; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR022122; DUF3657.
DR   InterPro; IPR007751; DUF676_lipase-like.
DR   InterPro; IPR044294; Lipase-like.
DR   PANTHER; PTHR12482:SF40; PROTEIN FAM135A; 1.
DR   PANTHER; PTHR12482; UNCHARACTERIZED; 1.
DR   Pfam; PF12394; DUF3657; 1.
DR   Pfam; PF05057; DUF676; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007303}.
FT   DOMAIN          803..996
FT                   /note="DUF676"
FT                   /evidence="ECO:0000259|Pfam:PF05057"
FT   REGION          430..531
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          588..612
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        500..531
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        591..612
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1072 AA;  118846 MW;  F0A13D503FF8B5F1 CRC64;
     MTEVQATVEF SVELHKFYNV DLFQRGFYQI RASLKVPPRV PHKVECSLLH PGGSDLAFPA
     SVQDDVICSK TFQILYKNEE VVVNDVLLFK VMMLLEEKKV EESLNEMDFQ LFLDLYFTDG
     DYTPDEPSSL QSISSRTLRL HFSLQRGIHQ HINVMFDYFH LAVVSVVIHA SLVALHQPLI
     SLPRPVKSTW LNRNAPAQSK DSAIPPLENV VFGSAYVKQV SPDGKTFLVS DHCLQHAFSL
     HHSLCSSLLQ TYQGLFGYFT AITKDLPSSH RMELEQLDLE ARLAELCEQV KKAESPDELA
     ELVNMNLAQL CSLLMALWGQ FLEVVSLQEH VTALLAVEHH TLRVRRFAEA FFCLEHPRQS
     ALAYQELHAH SHQQMTNAIK SSSYFLSLPP LPVESADLDG DVSSLPIIFE DRYLDSITEA
     GPEVFSRCSQ SAHKEEQVEH SGQKLPHWST GLKTETKPSI EDPLQGDTAT DLPHRTEIAQ
     RDQSSVQKPS PGVAEIPENT SAVSGVQSSL TSINSLPSDD ECEGSSKSVS VSGTELCGRK
     SSILVQEQSL VFSGEATGFV GILDTAVSDS QLMKPALSDA ELGLAGASSS GTIKDCHSEP
     TACPSSNSAT SSTDLVKRGM VENYFGSRSS TDVSEISPVE TSAITLGIQA EPQVREDEDE
     TEHEMIENGY YEEGDGYAFA NGVAEEGQSG VGDAGAHGTS VLFEQLGVGY LHETKDLSKA
     PICSNMLSSC VGHSLGRPLC LSAHRSFSLQ WYECAPTPQM KAFIKAREEL KQLRLPGFLY
     SEVPELASTV PYFSLEEDES CEDGIHLIVC VHGLDGNSAD LRLVKTYLEL GLPGARIDFL
     MSERNQNDTF ADFESMTDRL LDEIVQYIQL YNLTVSKISF VGHSLGNLIV RSVLSRPRFK
     CYLSKLHTFL SLSGPHLGTL YNSSALVNTG LWFMQKWKKS GSLLQLTCRD HSDPRQTFLY
     KLSKKSGLQY FKNVVLVGSL QDRYVPYHSA RIEMCKTALK DKQTGPVYAE MIENLLLPVL
     QNKDCNLVRY DVIHALPNTA NSLIGRAAHI AVLDSEIFLE KFFLVAGLRF FQ
//