ID H3CCJ4_TETNG Unreviewed; 528 AA.
AC H3CCJ4;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Fermitin family member 3b {ECO:0000313|Ensembl:ENSTNIP00000005967.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000005967.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000005967.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the kindlin family.
CC {ECO:0000256|ARBA:ARBA00008052}.
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DR AlphaFoldDB; H3CCJ4; -.
DR STRING; 99883.ENSTNIP00000005967; -.
DR Ensembl; ENSTNIT00000006115.1; ENSTNIP00000005967.1; ENSTNIG00000003380.1.
DR GeneTree; ENSGT00390000013444; -.
DR HOGENOM; CLU_011611_0_0_1; -.
DR InParanoid; H3CCJ4; -.
DR OMA; PNRRMIR; -.
DR TreeFam; TF314677; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13205; FERM_C_fermitin; 1.
DR CDD; cd01237; PH_fermitin; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR037843; Kindlin/fermitin.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR037837; PH_Kindlin/fermitin.
DR PANTHER; PTHR16160; FERMITIN 2-RELATED; 1.
DR PANTHER; PTHR16160:SF1; FERMITIN FAMILY HOMOLOG 3; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00295; B41; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303}.
FT DOMAIN 218..322
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
SQ SEQUENCE 528 AA; 60452 MW; 0E3634E1009C6349 CRC64;
LTDIRHPEEL SLLRPIEHKK KKKDKGSAEE VYDLTQVPLS SASKPCLYNG IPAHFADSPQ
MESVYKTLSV TQPPPSPETL AKRYRPASVV DKAHIHSRWL DSSRCLLQQG IQENDKVWLR
FKYFAFYEID PKYDTVRLAQ MYEQARWAIL LEDIDCTEEE MMLFGALQYH ISKVSLSEPQ
TASSSAAMDD LETALQSLEV KMEGESSSAA EMLDNLTAPE LNDYLKIFRP KKLTLNKYKQ
FWFKFQDTSI SYFKSKEESI GEPIQQIHLK GCEVAPDVNV AAQKFLIKLL VPAPEGMNEV
YLRCDDEQQY ARWMAACRLG SKGKTLADDS FQSEIQTIRS FLAMQRSGSN SHGNMPANDE
SINTHSLVSP RYHKKYKTKQ LTPRLLDAYQ NVSQLSLVDA ILRYLQIWQA LPDFGISYVV
VRFKGSRKDE VLGIAPNRLI RIDLSVGDVV KTWRYNNMKQ WNVNWDIRQV AIEFEGNINI
AFSCVTTDCK VVHEFIGGYI FMSTRSREKS NTLNEELFHK LTGGHEAL
//
