ID H3CF88_TETNG Unreviewed; 664 AA.
AC H3CF88;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Cyclic nucleotide gated channel subunit beta 1a {ECO:0000313|Ensembl:ENSTNIP00000006912.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000006912.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000006912.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; H3CF88; -.
DR Ensembl; ENSTNIT00000007066.1; ENSTNIP00000006912.1; ENSTNIG00000004285.1.
DR GeneTree; ENSGT00940000162283; -.
DR OMA; LVDYTCD; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.10.287.630; Helix hairpin bin; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45638:SF16; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL BETA-1; 1.
DR PANTHER; PTHR45638; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS00888; CNMP_BINDING_1; 1.
DR PROSITE; PS00889; CNMP_BINDING_2; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 476..580
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 602..624
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 664 AA; 74738 MW; AD2D18AD97F50524 CRC64;
PAPPLPVPAA PADGGAAAAP GAGASALRRR GGLSQISQSK LPAASAALSP RPRPLRLDSP
VPCPCRTRPL SAASVGSVLV QDRLNQLVSL FKGRTERQKE RLVDPDESEE DAPSACMGPV
DVSTRLQRSK VNQLGEALIV GFLISAAPSK ALVMEFRFPT SMDPYTDPVY VVWLFFVVAA
WNWNVWLIPV RWAFPYQTPD NIHLWLLADY TCDLIYIADI LLFQTRLQFV RGGDIVCDRK
EMRENYMTTD RFKTDLLSLF PLELCYIFTG VNPLLRFPRL LKYQVFFEFN DRMEAVMKKA
YIYRVIRTST YLLYSLHINA CLFYWGSAYE GLGATKWVYD GKGNAYIRCY YFAVKTLITI
GGLPDPTTVF EICFQLINYF VGVFAFSIMI GQMRDVVGAA TAGENYYRAC MDSTVKYMNS
YSIPQEVQNR IKTWYDYTWK SQGMLDEQEL LVQLPTKMHL DIAVDVNYTI VSRVALFQGC
DRQMVFDMLT RLKSVVYLPG DFVCKKGEIG REMYIIKQGE VQVVGGPDLQ TVFVTIRAGS
VFGEISLLAG GGGNRRTANV KAHGFANLFI LDKKDLAEIL VHYPESQKLL RKKAKMMLTK
DKKPELKDGG KETKDVIPPQ QETPKMFRAA LKVTEQAGME GTFAKLRGTY KEADASQVRQ
RQLQ
//
