ID H3CG47_TETNG Unreviewed; 378 AA.
AC H3CG47;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Sorting nexin 7 {ECO:0000313|Ensembl:ENSTNIP00000007224.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000007224.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000007224.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR AlphaFoldDB; H3CG47; -.
DR STRING; 99883.ENSTNIP00000007224; -.
DR Ensembl; ENSTNIT00000007382.1; ENSTNIP00000007224.1; ENSTNIG00000004575.1.
DR GeneTree; ENSGT00940000155315; -.
DR HOGENOM; CLU_040655_1_0_1; -.
DR InParanoid; H3CG47; -.
DR OMA; LHYYEEC; -.
DR TreeFam; TF328543; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0097153; F:cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0001889; P:liver development; IEA:Ensembl.
DR GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd06860; PX_SNX7_30_like; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 2.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR45949; SORTING NEXIN-4; 1.
DR PANTHER; PTHR45949:SF3; SORTING NEXIN-7; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Transport {ECO:0000256|ARBA:ARBA00022927}.
FT DOMAIN 36..157
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
SQ SEQUENCE 378 AA; 43546 MW; 3B6FC1D9BEAB0A47 CRC64;
QQASAEGASV PTCPSPTVNQ YRLDEDEEQL VDADVQDLLI SVDEPESHVT TIETFITYRV
VTKTTRSDFD CSEYQVHRRY QDFLWLRSRL EESSPTLIVH PLPEKFVVKG LVERFSADFI
ETRRRALQRF LARVAQHPLL SRSQHLRLFL TAPVGELQPH KKQGAGLLSR MGETVRAVAG
SLRGPRSRPE EFTLMHRYLE EFGSKISSVD KISRRISREQ REYLEELRRC APSYSLWAGL
EEELAEPLRG VATCVERCCL ETEHIQHLTQ VLVPVHEYVL GADTAKAVMR RRDVVHADYE
VKNEALALQV CGGDSWRRRW AAWRSVLELA NSALKEDWCR WQDSRRTDLR SAFLSAADGN
IQYYQKCLAV WESFLLSQ
//
