ID H3CKX7_TETNG Unreviewed; 267 AA.
AC H3CKX7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=AKT1 substrate 1 (proline-rich) {ECO:0000313|Ensembl:ENSTNIP00000008906.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000008906.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000008906.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H3CKX7; -.
DR Ensembl; ENSTNIT00000009077.1; ENSTNIP00000008906.1; ENSTNIG00000006158.1.
DR GeneTree; ENSGT00390000017397; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0032007; P:negative regulation of TOR signaling; IEA:InterPro.
DR GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; IEA:InterPro.
DR InterPro; IPR026682; AKT1S1.
DR PANTHER; PTHR21844; AKT1 SUBSTRATE 1 PROTEIN; 1.
DR PANTHER; PTHR21844:SF2; PROLINE-RICH AKT1 SUBSTRATE 1; 1.
DR Pfam; PF15798; PRAS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007303}.
FT REGION 99..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..138
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 267 AA; 28996 MW; 317A55A238E8B63B CRC64;
EPDIPDNHRD SWLALLSAAE AYSQKSGCDL AILTAWIPKD CEFSYSVWGQ GFLAESARRY
VDDISVLHST TMLMAQKHTR QAGGGGAKGL ADLRSEPGQV LAERERERGS QEAQRGRRRS
GIADVDEEGV RARERSAQRS RPFPPSGVFS MDEDSLSRDC EPFWSDGEEE STDGQWRPRL
PPAPLPAGGA VALARSLPVS VPAWSFRGTR GTQGDSGERH PQVGCADLDH IAASMKALLV
PGATDGTEMF GALPRPRLNT GDFSLKH
//
