ID H3CN11_TETNG Unreviewed; 402 AA.
AC H3CN11;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Serpin domain-containing protein {ECO:0000259|SMART:SM00093};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000009642.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000009642.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the serpin family.
CC {ECO:0000256|RuleBase:RU000411}.
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DR AlphaFoldDB; H3CN11; -.
DR STRING; 99883.ENSTNIP00000009642; -.
DR Ensembl; ENSTNIT00000009817.1; ENSTNIP00000009642.1; ENSTNIG00000006849.1.
DR GeneTree; ENSGT00940000158112; -.
DR HOGENOM; CLU_023330_3_1_1; -.
DR InParanoid; H3CN11; -.
DR OMA; KLTHAEH; -.
DR TreeFam; TF317350; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 1.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 1.
DR InterPro; IPR023795; Serpin_CS.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR000215; Serpin_fam.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR InterPro; IPR042185; Serpin_sf_2.
DR PANTHER; PTHR11461:SF84; PIGMENT EPITHELIUM-DERIVED FACTOR; 1.
DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1.
DR Pfam; PF00079; Serpin; 1.
DR SMART; SM00093; SERPIN; 1.
DR SUPFAM; SSF56574; Serpins; 1.
DR PROSITE; PS00284; SERPIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..402
FT /note="Serpin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003581413"
FT DOMAIN 54..397
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
SQ SEQUENCE 402 AA; 44447 MW; A9FC40997006C1A5 CRC64;
MKGTALLLVF AVLLSFCQAQ SETEAEETVA EEEHVELFTT TQTKMGAATS DFGYNLFRAL
ASQEVGNNVF LAPLSVSAVL TQLSMGASKH AQSQLFRALR YHTLQDPQLH DTLKELLAAV
RVPGKGLFAA RLYLSRRLQL KQDFLALVEN QYGVRPKAVL GKDLKEVNDW VSQQTGRKVQ
GFLASNFPRN SGANAVSAAY FQGKWVTRFG QSGLMDTFQV DNGAPVSIPM MKQDNYPVKM
GVDSDLQCTI AQVQMQNDVS MFLFLPDDVT SNMTQLEESL SAEFVQDLSM TLLPAQVSLA
LPVLRLSYSK DLLPLLGNLG LSDWLLNTEL EKISRQPVRL SSVRHKVVME MAPEGNQYPG
FSSAPSHLSY RVDRPFLYLI RDETSGALLF IGRVVNPTGL TI
//
