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Database: UniProt
Entry: H3CQI2_TETNG
LinkDB: H3CQI2_TETNG
Original site: H3CQI2_TETNG 
ID   H3CQI2_TETNG            Unreviewed;      2355 AA.
AC   H3CQI2;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   05-JUN-2019, entry version 52.
DE   SubName: Full=Immunoglobulin superfamily, member 10 {ECO:0000313|Ensembl:ENSTNIP00000010516};
OS   Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS   nigroviridis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae;
OC   Tetraodon.
OX   NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000010516, ECO:0000313|Proteomes:UP000007303};
RN   [1] {ECO:0000313|Ensembl:ENSTNIP00000010516}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15496914; DOI=10.1038/nature03025;
RA   Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA   Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A.,
RA   Nicaud S., Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B.,
RA   Dasilva C., Salanoubat M., Levy M., Boudet N., Castellano S.,
RA   Anthouard V., Jubin C., Castelli V., Katinka M., Vacherie B.,
RA   Biemont C., Skalli Z., Cattolico L., Poulain J., De Berardinis V.,
RA   Cruaud C., Duprat S., Brottier P., Coutanceau J.-P., Gouzy J.,
RA   Parra G., Lardier G., Chapple C., McKernan K.J., McEwan P., Bosak S.,
RA   Kellis M., Volff J.-N., Guigo R., Zody M.C., Mesirov J.,
RA   Lindblad-Toh K., Birren B., Nusbaum C., Kahn D., Robinson-Rechavi M.,
RA   Laudet V., Schachter V., Quetier F., Saurin W., Scarpelli C.,
RA   Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT   "Genome duplication in the teleost fish Tetraodon nigroviridis reveals
RT   the early vertebrate proto-karyotype.";
RL   Nature 431:946-957(2004).
RN   [2] {ECO:0000313|Ensembl:ENSTNIP00000010516}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   Ensembl; ENSTNIT00000010697; ENSTNIP00000010516; ENSTNIG00000007699.
DR   eggNOG; KOG0619; Eukaryota.
DR   eggNOG; ENOG4111N04; LUCA.
DR   GeneTree; ENSGT00940000158290; -.
DR   InParanoid; H3CQI2; -.
DR   OMA; CPLCMNP; -.
DR   TreeFam; TF326318; -.
DR   Proteomes; UP000007303; Unassembled WGS sequence.
DR   GO; GO:0021828; P:gonadotrophin-releasing hormone neuronal migration to the hypothalamus; IEA:Ensembl.
DR   Gene3D; 2.60.40.10; -; 12.
DR   Gene3D; 3.80.10.10; -; 2.
DR   InterPro; IPR000483; Cys-rich_flank_reg_C.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013098; Ig_I-set.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR013106; Ig_V-set.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   Pfam; PF07679; I-set; 4.
DR   Pfam; PF13855; LRR_8; 2.
DR   SMART; SM00409; IG; 12.
DR   SMART; SM00408; IGc2; 12.
DR   SMART; SM00406; IGv; 4.
DR   SMART; SM00369; LRR_TYP; 5.
DR   SMART; SM00082; LRRCT; 1.
DR   SUPFAM; SSF48726; SSF48726; 12.
DR   PROSITE; PS50835; IG_LIKE; 12.
DR   PROSITE; PS51450; LRR; 5.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007303};
KW   Disulfide bond {ECO:0000256|SAAS:SAAS01010727};
KW   Immunoglobulin domain {ECO:0000256|SAAS:SAAS01010457};
KW   Leucine-rich repeat {ECO:0000256|SAAS:SAAS00488662};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW   Repeat {ECO:0000256|SAAS:SAAS00597472};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     29       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        30   2355       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003581497.
FT   DOMAIN      470    567       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN      576    668       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     1373   1477       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     1482   1574       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     1580   1669       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     1680   1765       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     1773   1867       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     1873   1963       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     1966   2063       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     2069   2147       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     2164   2254       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     2260   2350       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   REGION      669    740       Disordered. {ECO:0000256|MobiDB-lite:
FT                                H3CQI2}.
FT   REGION     1162   1235       Disordered. {ECO:0000256|MobiDB-lite:
FT                                H3CQI2}.
FT   REGION     1286   1330       Disordered. {ECO:0000256|MobiDB-lite:
FT                                H3CQI2}.
FT   COMPBIAS    669    702       Polar. {ECO:0000256|MobiDB-lite:H3CQI2}.
FT   COMPBIAS   1162   1187       Polar. {ECO:0000256|MobiDB-lite:H3CQI2}.
FT   COMPBIAS   1212   1235       Polar. {ECO:0000256|MobiDB-lite:H3CQI2}.
FT   COMPBIAS   1286   1301       Polar. {ECO:0000256|MobiDB-lite:H3CQI2}.
FT   COMPBIAS   1311   1330       Polar. {ECO:0000256|MobiDB-lite:H3CQI2}.
SQ   SEQUENCE   2355 AA;  261318 MW;  1A2D478444FFE7B7 CRC64;
     MSVRACGASY LQRWLLRLLF FLAATSSEGA DCPRACVCNV PSEMHCTFRY LAAIPDHIQP
     HVERINFGYN SITALRENDL LGLGKLELLM LHSNKIVDIE DNTFQNLRSL QVLKMSFNKI
     KKINKGTLKG LENLMRLYLD HNQIEFINPE AFYGLTNLQL VHLESNHLQQ IHPDTFITMR
     HNQVFKVSSV RTLHLSDNQL KTLPADAFSG CSKLENLFLH SNPWACDCRM SWFAHWAKKN
     PGLFKCKRDK RYPNGLLCPV CQNPVPYNNR NLFLLPVDAF TCSKPWIDPH LKQRNITVDE
     GDFTPVSPRD FIAPLGTIQM NLSNQFQSDA SLSCSVQRPS AFENLNQTLE VEEGNNVILL
     NADITSYLVC NVEHDHIQRL WQILATYSDA PMRLERGSLL TRTPEMVYQY SEIKTEEGLQ
     TNVEAEIKAS PAWLMQGELS FQLDRTSTTY TTLHIRYQSM VTLRVETTSP KKSHYSWTMI
     KRDNETKTEH TVVRGGVANL NCQIQGEPKP LLEWILPDGS KVRAPYSSED RRIVIYGDGK
     LTLTSTDTSD AGMYRCIATN YLDADILVFR LMVLSPDVEE DEVNGVKLSS PLGGNQVLDC
     SFSGSPKGSV QWILPDHSVL DVSHGSKTLY ENGTLEIQGL TERDRGFYRC IAANNLGVDL
     LVSQLTLTEE KTGPESEGSG MTDETPSSTP YSRSTAGSQK TPPDPPESRH RSQGRGAGRK
     WGQKRGPSIN RRPWSGRVFD KASRKIEQQK FAEFVKKAKK GTGVKSGTIP NINDDNETGS
     TVELIEDQLI IATDSPLGVT VSAKEQQTIT TTIEAENKNI PATQMYKQPN YKPVYINLDE
     HSELDSSQET QIQFTAQPAE PETSTWGGVL FTTDPYVTPM SDSVGPRNVV VHTDSEHQTL
     FATTTTTESQ QDGILFHTTQ TLKSPHLLAG STIISKQQIH IIPDKNNGSG GHRKIFHSRR
     RIIKPSRITN IQSFLNQLKQ SSNNKKSIGT TGAPTIKTTK NPVQQTTLSF QSSAITGTSV
     SKIIHRKIPW NRLFGNKNKE KILGRLKKPF ISQKLTTRSM AETKTTSIVT KPTDVFTTDF
     IPINSMDGKD ILSPFRNTKR KDGFSGDDYE GLSLSKCEST TLRPGSNQVT TATPPYQRSF
     TTAANPPGLL ILPSPPTVIT PSSEKVISSG SGGTPDILLT SRQSPGWKGQ KRKIFRGRRP
     LIRPGLGLHP SRTSKPSATG NKMETTMPQH GTYSPYKPLN KNVNLYDKTY WTSSNSTLAY
     TTTMRPLIPS TTLNPTTTLR PTTLHTKVNN TKPTTWNKKI QTHRPQVKRN KPTVKSSSSQ
     ESKKRPPNLE TLTISTLEPK YTSTPATYNI VSASSSFYNA SEIDITSSSI QVPEVTTKLL
     MNRPKIIGGN AASYTVLSHS NAYLPCHSIG NPQPTINWRR LSSTTGNSII IKGKMGKYEV
     LHNGTLSIHN TNIKDRGQYL CTAENDHGMD KLLVTLSVVA YPSRILEPKL RQIKVLAGNT
     AEVTCKAEGR PTPSISWILP NRTQVRGLNT EWGRVSVTPE GALVIKDLSM NDRGHYKCIA
     SNQAGGDIAT VQLHVVAAPP GIMEEKRQQV NIGVSQSALL PCTGQGRPQP TIHWVLHDGS
     HLPSKRLTSN TRTLVHENGT LYIENVTQAD SGKYECIATS STGSEKRVVI LVVEKAASAP
     HIVETFQRKM ELFFGDQLRL NCSAVGDPRP KIMWRLPSKA MLDQGHRDNG TLLINSVTDK
     EAGHYLCVAR NKIGDDAKLI RVSVSMKPAK IEPKLYEKKE VTYGNGVKVD CKASGAPKPE
     ISWGLPDGTM VSSAFQADVS SGGQAQRYTL FDNGTLYLNQ VSISEEGDYI CYAENHLGKD
     EMTVHISVMT VTPVIHPPSQ TYARVKPGGS IRFDCEAVGE PKPKIFWMLP TNDVIAASNE
     RYLVHVNGSL DIRDIRVSDT GEYVCMARNP AGENRKVYKL DIDGNPPVIN GHRQNRTVIK
     DVAAKFSRKL IDCKAEGNPT PSITWIMPDN IFLTVPYFGS RINVHRNGTL EIRNVRPTDT
     AEFICLARND GGEAVMVVQL EVTGLLRRPI FKNPFNERIV SQIGKTIILN CSADGHPSPQ
     IVWTFPNGTR FSNKAEHGSH FHIRKDGSLV IRPGKEDAGN YRCGARNYMG YIEKLIILEV
     GQKPYIMTRP RGVIRSVSGE PLFLHCLSDG SPTPKIYWTI PGGHTLSHPQ ILGRHQLLEN
     GTLVVEHTTL HDRGNYICRA RNDAGEAVII VPVVIVAYPP RITIGPLPNV KATRGTPLQL
     SCAAIGIPKP EITWELPDRS VLSSTQQGRP TGGELLHPQG TLIIQRPSVS DTGRYKCLAK
     NYLGIDSKVT YVRVL
//
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