ID H3CQY1_TETNG Unreviewed; 535 AA.
AC H3CQY1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=ArfGAP with FG repeats 1b {ECO:0000313|Ensembl:ENSTNIP00000010665.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000010665.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000010665.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H3CQY1; -.
DR STRING; 99883.ENSTNIP00000010665; -.
DR Ensembl; ENSTNIT00000010846.1; ENSTNIP00000010665.1; ENSTNIG00000007845.1.
DR GeneTree; ENSGT00940000155511; -.
DR HOGENOM; CLU_027801_1_0_1; -.
DR InParanoid; H3CQY1; -.
DR OMA; MANMQPG; -.
DR TreeFam; TF325357; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08857; ArfGap_AGFG1; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR46134:SF5; ARFGAP WITH FG REPEATS 1B; 1.
DR PANTHER; PTHR46134; DRONGO, ISOFORM F; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}.
FT DOMAIN 11..135
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 165..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..189
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 535 AA; 56848 MW; 6ACFB61FB4075BE9 CRC64;
MATSAKRKQE ETHLKMLREM TSLPANRKCF DCDQRGPTYV NMTVGSFVCT TCSGILRGLN
PPHRVKSISM TTFTAQEIEF LQKHSNEVCK HIWLGLYDDR TSVVPDFREP QKVKEFLQEK
YEKKRWYVPP DQARAVQVSV SGSSASSTGS TPEVQPLKAL QLNKTPLRQV NNSPPVAQSP
GLPRSQPHST TQEKKFDLLS DLGGDIFAAP PTHTSNSANF ANFAHFPSQS AHQVNSNANF
ANFDAFGNTA IPSHLNTSPP SKSLSSGISI LPFPVFHFIH TLCGSGEIFF TLVQFFSKAV
DLLPGSTEVR FDATFVSVMN EYHILVSSGG TVPIPSVSSA VPAQSQLGGQ LEDRYAAAEL
DNELSTVSTG SSVQGNIFGP VLGSSPAQNP PVLPSMQPGF GAVPSTNPFV AAAVAPEMAT
NPFQTNGRAP AAASFGTGSM SMPAGFGNAS SYCLPTSFSG NFQQQFPGQA PIPYSQPGAY
HPQSNASIMG LGNVNVLGTP FGQPMAGPSM SNNPFMAGAP AGSFPSGGSS TNPFL
//
