ID H3CSC5_TETNG Unreviewed; 734 AA.
AC H3CSC5;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Interleukin enhancer binding factor 3b {ECO:0000313|Ensembl:ENSTNIP00000011159.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000011159.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000011159.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; H3CSC5; -.
DR STRING; 99883.ENSTNIP00000011159; -.
DR Ensembl; ENSTNIT00000011341.1; ENSTNIP00000011159.1; ENSTNIG00000008329.1.
DR GeneTree; ENSGT00940000156719; -.
DR HOGENOM; CLU_015490_0_0_1; -.
DR InParanoid; H3CSC5; -.
DR TreeFam; TF320194; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.1410.40; -; 1.
DR Gene3D; 3.30.160.20; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR006561; DZF_dom.
DR InterPro; IPR049402; DZF_dom_C.
DR InterPro; IPR049401; DZF_dom_N.
DR InterPro; IPR043519; NT_sf.
DR PANTHER; PTHR45762:SF4; INTERLEUKIN ENHANCER-BINDING FACTOR 3; 1.
DR PANTHER; PTHR45762; ZINC FINGER RNA-BINDING PROTEIN; 1.
DR Pfam; PF00035; dsrm; 1.
DR Pfam; PF20965; DZF_C; 1.
DR Pfam; PF07528; DZF_N; 1.
DR SMART; SM00358; DSRM; 1.
DR SMART; SM00572; DZF; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR PROSITE; PS50137; DS_RBD; 1.
DR PROSITE; PS51703; DZF; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00266}.
FT DOMAIN 1..296
FT /note="DZF"
FT /evidence="ECO:0000259|PROSITE:PS51703"
FT DOMAIN 323..389
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 279..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 690..734
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 289..304
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 690..713
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 734 AA; 80521 MW; 0625F61BA4D5C248 CRC64;
DQATRTLRGV MRVGLVAKGL LLKGDLDLEL VLFCRDKPTG SLLRNVSENL VTQLKLVATE
DKYVVTAHLN EACIIIKNSK EPPLALTIHL TSPVVREDVE KVAAGESLSV NDPLDVLDRQ
KCLTALASLR HAKWFQARAN GLRSCVIVIR ILRDLCARVP TWTPLHGWPL ELICEKAIGT
GNRPMGAGEA LRRVLECLAS GILLADGAGI SDPCEKESID AINHLNLQQR EDITISAQHA
LRLSAFGQLH KVLGMDPLPS KMPKKPRSET SIEYTVQIPP STTYTPSMKR PIEEEDGMGD
KSPNKKKKKL QKKSPEEKAD LPQTMNALMR LNQLKPGLQY KLVSQTGPVH VPVFTMSVEV
DGTVFEASGP SKRTAKLHVA VKKPQVLETQ LLHLAEDEVC EVVEEAGHSI MAKEVLPLDV
DLELMVTATV DTPQDSISLC QVLFLFQTTI FLLGRLFSGM TYLSVTGAEK SKSYKVQTSV
ATMILQHRSS STMCTGFFFS LFLLFIFPRS PDTKMGCAPE TVVCKVSCLS NEPAPKNSIP
NLKKNKKKTT KTRALFVLHQ FGFNKEVQRY HNSHREAYYY NYDGKNGEGG LSKSPSAQGS
YYQSDGHCIP LSAAKALKKK PTIHKGAKPL FQSSVLGQAS FNQYGQIYGQ GKRGFSQNQG
GTDAYTCNTA YPIQVTGGAG GSQEYNYEGF SSQSNYNSQG SGEGGNQGFG ANHSQYHDPG
GYSRGDAGMN YQYR
//
