ID H3CTG9_TETNG Unreviewed; 604 AA.
AC H3CTG9;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=MSL complex subunit 2 {ECO:0000313|Ensembl:ENSTNIP00000011553.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000011553.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000011553.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H3CTG9; -.
DR STRING; 99883.ENSTNIP00000011553; -.
DR Ensembl; ENSTNIT00000011735.1; ENSTNIP00000011553.1; ENSTNIG00000008703.1.
DR GeneTree; ENSGT00390000016814; -.
DR HOGENOM; CLU_038772_0_0_1; -.
DR InParanoid; H3CTG9; -.
DR OMA; TEVCDSN; -.
DR TreeFam; TF328848; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0072487; C:MSL complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR CDD; cd13122; MSL2_CXC; 1.
DR CDD; cd16522; RING-HC_MSL2; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR037922; MSL2.
DR InterPro; IPR032049; Msl2-CXC.
DR InterPro; IPR032043; Msl2_Znf-RING.
DR InterPro; IPR033467; Tesmin/TSO1-like_CXC.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR16048:SF3; E3 UBIQUITIN-PROTEIN LIGASE MSL2; 1.
DR PANTHER; PTHR16048; MSL2-RELATED; 1.
DR Pfam; PF16682; MSL2-CXC; 1.
DR Pfam; PF16685; zf-RING_10; 1.
DR SMART; SM01114; CXC; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 61..102
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 278..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 419..474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..304
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 441..455
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 604 AA; 65309 MW; E36F57D2D5ED02C7 CRC64;
THSYLPNRSR ALGRAAEMNP VNATSLYVSA SRSVLQCDPR DPRALAELCK LLPFFRQSLS
CLVCGNLLQD PIAPTDSSCQ HYVCRGCKGQ RMQLKPSCSW CKDYSRFEEN KQLSLLVHCY
RKLCLYITQS PLAPHVASAA SNSPDLQAIL SEGLTLAEGE TKAEDNSESL SLMQSASTST
LCQTDNSHLT KEFKVEEPSS ISVNGLHDCN GLVSLDSLQH ITIENRRGNS ETEIPVCVSV
TGTGDVGLCE ISSFGDDLKH GGGPLLLSVE EVLRTLETDT DPEPNPHADC QPSMHQSSLN
GPHYPAGNSP HLLQPHTQTT LHVPPQPSPA IPRIPPRYHR KRSHSESDSE KVQPLPISSL
LRGCPLGTIG SPQHPNPTAT IKQELKYPAA TPQPHLAPVP NGSPPKVGKT VLVTNKTLKK
TVEHHGAPKK AYTKARQGAP KPRAQPRDRV PSHPHAHPLT HPPSPSKPQY KKPVEKKGCK
CGRATQNPSV LTCRGQRCPC YSNRKACLDC ICRGCQNSYM ANGEKKLEAF AVPEKALEQT
RLTLGINLTS ITAAALRGPA TSSPGNTLLN VTTATGAPVT ATFLSSAGHD SRGFDDSLEM
QFDC
//
