ID H3CUV8_TETNG Unreviewed; 1487 AA.
AC H3CUV8;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Nucleoporin 153 {ECO:0000313|Ensembl:ENSTNIP00000012042.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000012042.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000012042.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 99883.ENSTNIP00000012042; -.
DR Ensembl; ENSTNIT00000012233.1; ENSTNIP00000012042.1; ENSTNIG00000009182.1.
DR GeneTree; ENSGT00940000153253; -.
DR HOGENOM; CLU_004629_1_0_1; -.
DR InParanoid; H3CUV8; -.
DR OMA; SASEWEC; -.
DR TreeFam; TF323517; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR Gene3D; 4.10.1060.10; Zinc finger, RanBP2-type; 4.
DR InterPro; IPR026054; Nucleoporin.
DR InterPro; IPR013913; Nup153_N.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR036443; Znf_RanBP2_sf.
DR PANTHER; PTHR23193; NUCLEAR PORE COMPLEX PROTEIN NUP; 1.
DR PANTHER; PTHR23193:SF23; NUCLEAR PORE COMPLEX PROTEIN NUP153; 1.
DR Pfam; PF08604; Nup153; 1.
DR Pfam; PF00641; zf-RanBP; 4.
DR SMART; SM00547; ZnF_RBZ; 4.
DR SUPFAM; SSF90209; Ran binding protein zinc finger-like; 4.
DR PROSITE; PS01358; ZF_RANBP2_1; 4.
DR PROSITE; PS50199; ZF_RANBP2_2; 4.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00322};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00322}.
FT DOMAIN 656..686
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 726..755
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 795..824
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 854..883
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 47..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 174..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 380..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 434..472
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 616..646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 685..714
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 882..904
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1010..1280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1346..1397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1427..1448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..82
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..110
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..467
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 625..646
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1032..1073
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1170..1199
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1207..1224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1261..1280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1360..1374
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1375..1397
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1487 AA; 149698 MW; 4C20B0984657D7AD CRC64;
GGGKISSRRY HIASKPYAKS KQQQQSRLIS RVTDTVKSIV PSWLQKYFNN ENGPEGGGSD
QGRDENCQLP PSPPPQPPNG NEEGPPVDGR DSPEPSTSNT ATEPTTSRAS LNFQEFVLSR
PPLNRSHLHF TPLDVSSPNL GNSNSLFSQP SMSSAPGPFT TGFSLVKEIK DNLSQHEDDN
ISTTSGFSSR ASDKDVPTTK TASLPQLWSP EMDRSHTGPQ PSQSSMKKPA FNLSVFGTSS
NASFNNTVLN SSRLGDSPFY PGKTTYGGAA AARSSRNRPG TPYQAPVRRQ IKAKPAGAQP
CGVTSATARR VLQSLERMSS PLADARRIPA SASSPLSRTM DSINLDALHS QAKKKRMDIT
LPPVQKLVVP SVAPVSGNRS MSFRPTLTPG GVSRPLDKTP ASLEETGPCR NWDTSQDRGT
IGYSAPAYPL SSTPAANSVT CGGGKMKRER SSMRASSKRH EEDEVPELPD LPPISLPISS
TTALPTFSFT SPLLTATISS TPSVTVTPAK SQEVKIKTTP ALSPPSVPFT FSSPIVKATP
ASTPSFSPSA GFTFSAPVAK GPSISIGKLA NPKVAAGKFF VFPVKPATSK STDVSDGLFK
PAKTLKQGSV LDLLKTPGFS SPVPTGPAPQ QTAASPPATT TTSSTSSSAG FGDLFKAVPG
WNCDVCLVQN KPSDTKCVCC MTPQPESSSS APSDGKPPAA SSAGPESSSS TSTTTTAGFA
AVFTKPAGSW DCDTCLVRNK SDAVKCVACE TAKPGTGLKT SLTIPSAFSA IKAESAPASP
ASTGFVGFGD KFKKPEGAWE CDTCMVENKA EDTKCVACMN TKPEKGASAE ASAEASTPAS
AAPVLGFGDA FKKPEGSWEC DVCLVQNKAA DGACVACQTS RPGAKAEPKA GGPSSSSTFG
SSTSGPGGFK FGTSESSSAS VSQGFKFGAS FGDSSAPATG FKFGAAFGSS SSEPASQGSS
ASSGFKFGGS SEGFKFGTAS NDEKPACQPA AASGFKFGTA GVVFGTGASS TESEGGFSFG
VAKAEEKTPP ATAASSVGSP AAPQEKSESL ATTSDAVSNV TATSESTTTA AKGSVFAKLG
GPSSAAPAPQ ADSLFGSSAA NKEPAAPTFT FGKPEEKKDV APSPAPSGFV FGGANKDGNS
APAPATTGGF TFGKPGAPSE PPPPVFSFGK SADTNPSNAP KPEFSFLVSN PTNPTTTAAA
AAAAAAAASS SSITTQSLFG GSAASSQPPA PPAASGAFVF GQPATSSGDG PPAKAAFVFG
QGQESQASAP PAAALNSTAS PSPAQPFIFG VSASGAAPPA AAPSFGFGAA APSATSSSGL
RALVSPSAAS SPFTFSSAPS GGFGAGPAPS FGPSFGSPFT APPSQSPPTF GASPNPTPVF
GQQANSTPAF GAGANSSSGG GFQFRASGFG ATNNTSSVFT FGAGAAASPA PPANPAIPPQ
TGATGAGFSF AQAPAFNIGS TKSFTASPAG QQAIAGRKFK MAVRRRK
//
