ID H3CVM0_TETNG Unreviewed; 1181 AA.
AC H3CVM0;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=PDZ domain-containing protein {ECO:0000259|PROSITE:PS50106};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000012304.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000012304.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H3CVM0; -.
DR STRING; 99883.ENSTNIP00000012304; -.
DR Ensembl; ENSTNIT00000012495.1; ENSTNIP00000012304.1; ENSTNIG00000009433.1.
DR GeneTree; ENSGT00950000183159; -.
DR HOGENOM; CLU_277024_0_0_1; -.
DR InParanoid; H3CVM0; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0030155; P:regulation of cell adhesion; IEA:InterPro.
DR GO; GO:0023051; P:regulation of signaling; IEA:InterPro.
DR CDD; cd00136; PDZ; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR031865; DUF4757.
DR InterPro; IPR029978; LMO-7.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR46767; LIM DOMAIN ONLY PROTEIN 7; 1.
DR PANTHER; PTHR46767:SF2; LIM DOMAIN ONLY PROTEIN 7; 1.
DR Pfam; PF15949; DUF4757; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303}.
FT DOMAIN 958..1037
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 93..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 150..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 642..663
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 696..726
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 773..795
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 828..879
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1062..1095
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1138..1177
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 93..108
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 642..657
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1077..1095
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1181 AA; 130965 MW; E6724FAC3FDA20A9 CRC64;
DNVSVFLKAC GKLGLNVSQL FDPGDLQDLS NRVTLRHNES KRRLKNVLIT IYWLGRKAHL
DAYYSGPQLN FKAFEGLLGL ALSRALDEGA NLKDGWCPER EEDTQPRRSC RSQTSVDSIE
SLEPRNLTSC ASEIVGCGSD AEAEQVFKME TTQDSPRWSR GRIPPLPPQR KQNSPAPAPL
PGTATIQNEL LVNTLGCDNL CYSNEERPSY APQTPLAIIS SSDLSVIEET FFQALSEEDS
DDDFAEADPV QDDLYFRRLQ QTRRQTSSCP RFDRFLPQYW TPEEEARVHT IYLGSRRRPW
YHKMQQLSQR ALRSTMEECS TDFFSWFLAS RTVPPGSAEV QNLSADLKRG SYAEASAGFA
LVCSACMLKK FEKLSDAHHN FWEIKPRILT TLNLVPPITL LKANLLTATQ LSRLTFCRPQ
PRYYLVQVLA AVIPTAAAAA ICSVTLLDFA RCSPAHTWLR SLLLGCRMCH IAAVIRMQCN
GAVMSSVQSV VFGSVDLFQL SASLSVLTRS KSLSDIPMVY PVCKVPNGRM VNDVRGENGV
ASDWNHGKPQ CTTVAEDAEA QWQDDLTKWK NRRRSTKSDD CRKSQDREHV IHQMTNSAET
NFEKNEAGVP LERCSYDILL FKPRTRAPLT RSYVTEVILS PASSVRPHSS SDAHRSTAGA
MPASDGTILV EDTPFASLAS EGAGVTTPSL EFPFSSQTQV KGQSSPAPMQ PSSKPADSEK
GPTSQISSLV TTLQPNGATA AFDKDPTELC AGPKVPPFFP DEVHQASVYT TDNRHNLSTS
GTSMEHSNGQ QAGGSRKYFA QMGSWAHSAS LPRGYRRSES SCRLSSAITA RPYSSRQSKA
SSLPRLQHVD DNQGLLSKQK NDTRVDQSGG EQLGAATDAT PFQTQSPLQV GLILQDNPGE
SPTLPSAPCS DHTKAASARK SFITFMVLVS VRKHRTPNLR VLHFLCAFQV GHSVMRVSLT
LKPDSRSDFG VQTHWDSTGA RVQFIQPGSP AELCQLRVDD EIVALNGVSV AHMSSSQWME
KLTSSLRAGS LTMDVRRYGN KVSPNLFEMI CDIFNPEFPS TQTDCPTRPA SHGNPAENPI
GTASELSGQT NGASGRLELR NNHKRRAEFF QTGGSESAIS DLQVPSLSPS TSSWMWNYEE
ERKRQQKWQE EQERLLQDKY RRDQRRLEAE WQRAQQDAME E
//
