ID H3CVQ2_TETNG Unreviewed; 873 AA.
AC H3CVQ2;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Protocadherin 20 {ECO:0000313|Ensembl:ENSTNIP00000012336.1};
GN Name=PCDH20 {ECO:0000313|Ensembl:ENSTNIP00000012336.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000012336.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000012336.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H3CVQ2; -.
DR Ensembl; ENSTNIT00000012527.1; ENSTNIP00000012336.1; ENSTNIG00000009464.1.
DR GeneTree; ENSGT00940000156743; -.
DR HOGENOM; CLU_006480_5_2_1; -.
DR InParanoid; H3CVQ2; -.
DR OMA; IEHPAMD; -.
DR TreeFam; TF320624; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 7.
DR Gene3D; 2.60.40.60; Cadherins; 7.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF260; PROTOCADHERIN-20; 1.
DR Pfam; PF00028; Cadherin; 5.
DR Pfam; PF08266; Cadherin_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 7.
DR SUPFAM; SSF49313; Cadherin-like; 6.
DR PROSITE; PS00232; CADHERIN_1; 3.
DR PROSITE; PS50268; CADHERIN_2; 7.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 810..834
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 18..131
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 132..242
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 243..348
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 397..457
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 458..561
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 562..664
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 668..791
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
SQ SEQUENCE 873 AA; 97400 MW; 0970CB930B9DA497 CRC64;
YIVLLYSSPP FCLANFNQAK ELIYKIKEGL PKGTYIGAIG LDLNLDFTVD PPFSFSFAQK
KVNEQYVFLN NTSGELYTTA TEIDRETLCP DSHEQWGCIL PLDVFVLPQQ YFQLVKVKIL
IQDVNDNRPK FPVDQISITI PENALVNTRY AVEQSAMDPD LGVHGVQTYW LVNDFGVFTL
DVEENDGGEL TPFVIVTEAL DRETQAEYVT DIIAEDGGTP PLLGAATLII LITDVNDNCP
QFTESQINVT LHGNASKGTH LARLHAFDPD LGANAQISYA YSERMPRDTR SLFHLDKITG
VIKLAKKLDT GATTFYKLTV LANGPGCIPA VSTIHVNIIK IVTGPPAVIT RYIAPEKDGV
VTLKESEPAF SPIAFFTVKN IGINQKVECY LEGSGPFRLT PYQLLRNEYL LETTENLDYE
KIRDYELVVV ARKTQDLVIK TFLKVQVLDE NDNAPVFEQS LVKILIDENN SPNTFLTQLQ
ATDQDSEERG EVVYLLGGDA PEIFVLDRVT GVLTVATSLD REEKETYRFI VRAVDKGTPK
RESIATVVLT VQDRNDNSPR FLNKDFTFFV PENFPGYGEI GVMSVTDADA GENGWVALSI
VNGSDTFMID TGRGALRAKT SLDREQQGTY QLWIEAVDGG EPALSCVTMV TVLLLDVNDN
PPIVLFPQSN QSYMLVLPST LPGTSITEVY AVDRDTGMNA VIAYSIIKRK GGDPGSFAID
PETGNITLKR ELSNRGLHSL LVKVSDHGQP EPLYSTVMVN FFVNETVSNE SYIQSLLTKE
ADIEVEERPW YISRMREGPE RYESLNCQPV LIVLSVMCLG LFFLVIMLTS FLCLRRFKKH
RKKQSEAEIP LKMKNDLAQG VNRKIRQADL KHL
//
