ID H3CWY0_TETNG Unreviewed; 409 AA.
AC H3CWY0;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=SET domain containing 4 {ECO:0000313|Ensembl:ENSTNIP00000012765.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000012765.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000012765.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H3CWY0; -.
DR STRING; 99883.ENSTNIP00000012765; -.
DR Ensembl; ENSTNIT00000012957.1; ENSTNIP00000012765.1; ENSTNIG00000009875.1.
DR GeneTree; ENSGT00940000153577; -.
DR HOGENOM; CLU_029120_3_0_1; -.
DR InParanoid; H3CWY0; -.
DR OMA; ISHMKDE; -.
DR TreeFam; TF106421; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd19177; SET_SETD4; 1.
DR Gene3D; 3.90.1420.10; Rubisco LSMT, substrate-binding domain; 1.
DR Gene3D; 3.90.1410.10; set domain protein methyltransferase, domain 1; 1.
DR InterPro; IPR015353; Rubisco_LSMT_subst-bd.
DR InterPro; IPR036464; Rubisco_LSMT_subst-bd_sf.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR044429; SETD4_SET.
DR PANTHER; PTHR13271:SF163; SET DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR13271; UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE; 1.
DR Pfam; PF09273; Rubis-subs-bind; 1.
DR SUPFAM; SSF82199; SET domain; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 280..391
FT /note="Rubisco LSMT substrate-binding"
FT /evidence="ECO:0000259|Pfam:PF09273"
SQ SEQUENCE 409 AA; 46748 MW; 0E895391C2BEFF85 CRC64;
RCRAGRAARK RRHKQESAIQ SVSSVSLCHQ HKYVRLMRFL HQRGFSTRLL QPSAFTDTGR
GLQVLKNVKP GQMLISLPES CLLTTSTVLN SYLGPFIKGW KRQVSPLLAL CVFLMCERHR
GEARIGPYID VLQLHHLPIY FLKEANQFRS LQTILSQPVE DVLTYEALRW AWCSVNTRSV
FMSHPSDTVL RGQDVYALAP FLDLLNHRPD VQVRAGFNEV TKCYEIRSVS GILRYQQAFI
NYGSHDNQRL MLEYGFVAPR NPHSVVYVDK DLLADVLRGD QSLEQKLKFL RQNHFLHNLT
VSGEGPSWRL MTALRLLSLP QTLYHHWRGV LLGQAVCEER EGWSIQTAKT LCHRLLADTH
TALEQISNIQ QCEQSVREQL SVAAALRQEE RCLLASCLQA LAESRTSGH
//
