ID H3CY68_TETNG Unreviewed; 646 AA.
AC H3CY68;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Myotubularin related protein 11 {ECO:0000313|Ensembl:ENSTNIP00000013203.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000013203.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000013203.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC receptor class myotubularin subfamily. {ECO:0000256|ARBA:ARBA00007471}.
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DR AlphaFoldDB; H3CY68; -.
DR Ensembl; ENSTNIT00000013395.1; ENSTNIP00000013203.1; ENSTNIG00000010300.1.
DR GeneTree; ENSGT00940000160276; -.
DR HOGENOM; CLU_021912_1_0_1; -.
DR InParanoid; H3CY68; -.
DR OMA; CRDMRVL; -.
DR TreeFam; TF315197; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR CDD; cd14595; PTP-MTMR11; 1.
DR InterPro; IPR010569; Myotubularin-like_Pase_dom.
DR InterPro; IPR030564; Myotubularin_fam.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR PANTHER; PTHR10807; MYOTUBULARIN-RELATED; 1.
DR PANTHER; PTHR10807:SF51; MYOTUBULARIN-RELATED PROTEIN 11; 1.
DR Pfam; PF06602; Myotub-related; 2.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51339; PPASE_MYOTUBULARIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007303}.
FT DOMAIN 165..637
FT /note="Myotubularin phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51339"
SQ SEQUENCE 646 AA; 73222 MW; 727914DE3F380E89 CRC64;
SSRGRDVFGL RCLPDVGECV LQRAVMVRKK LTAKEGRGWL SGTLFCTHFR VAFVPELIQD
NADPVLLGDH DVALASIEKV VVVGPNRTKV VTPNSSLKFT PEELLLYCRD LRVVCFLFDR
LTPDAQVLEV LLRFEAQAKA SDSVGRQEMK QFLSNRRREA HMNWFESAAD WEQELDRCGA
TGWRVSSVND RFEMSTSLPR FVVVPQKVLD TELKKSFAHF NEGRIPRWCW RHPWGSDLLR
MASFQNNIYH EKDDIRNLEM ILFGCQSSLC VVVELGDELP SPTDIQLAHG RLRALCLGDI
STSVSVPDDK WLSTLESTRW LEYIRSCLKK AAEVACLLRG GHLTVALQEA EDRDMSCVVS
SLVQVMCDPH CRTQYGFQGL VQKEWVMAGH RFHSRMNYHR DNDKEEAPVF LLFLDCVWQL
LSQFPSHFQL TGDFLLALHD SIQLPLFTSF MANCQRERCK RSQNLGQLYT PVNGWRDVLH
PDSPSDPSDP PLPSVWDWAL QYSKHRRDRF TQPVLPVARL QPLLNGNLNT NPDTRRLLDS
ITGSVFLFSH GTFSCPANLL PWRSGGGGSS GVYKKSHRRV ASSESVPGLE RLLKAWNLTE
SPQGLALRPS PPGQPDPHQP LIPLLMGPCM GLWRECYLRG ALHAQV
//
