ID H3D1T7_TETNG Unreviewed; 1633 AA.
AC H3D1T7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=Myosin motor domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000014475.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000014475.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR Ensembl; ENSTNIT00000014674.1; ENSTNIP00000014475.1; ENSTNIG00000011525.1.
DR GeneTree; ENSGT00940000163461; -.
DR HOGENOM; CLU_000192_8_1_1; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR Gene3D; 1.20.5.340; -; 4.
DR Gene3D; 1.20.5.370; -; 5.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 2.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF44; MYOSIN-13; 1.
DR Pfam; PF00063; Myosin_head; 2.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 4.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 2.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000007303}.
FT DOMAIN 33..82
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 86..293
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 323..481
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 358..380
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1579..1633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 543..593
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 727..852
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 889..930
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 966..1528
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1579..1626
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 180..187
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1633 AA; 187714 MW; 6AE0651AB1C27D4C CRC64;
MSSDSEMAVF GQAAPYLRRP ERERIEAQNR PFDAKTAVFV VDPKELFVKG TLLSKDGGKA
TVKTCKGQVV TGREDVIFLR TQCNIVKVNL SCIKTNGENC CVKSYLKPVI YSDILQTYSG
LFCVTVNPYK WLPVYNQEVV WAYRGKKRQE APPHIFSISD NAYQFMLTVD RENQSILITG
ESGAGKTVNT KRVIQFFATI AGLGDRKKEP ISSGKLHGNL EDQIISANPL LEAFGNAKTV
RNDNSSRFGK FIRIHFGTTG KLSSADIETY LLEKSRVTFQ LSAERSYHIF YQITSNKKPE
LIGNIKHNKL NNPMTPRCFF FFLFPIXDAS GGAGAGKKGA KKRGSSFQTV SALFRENLGK
LMTNLRSTHP HFVRCLIPNE TKTPGIMEHH LVIHQLRCNG VLEGIRICRK GFPSRILYGD
FKQRYKVLNA SVIPEGQFID NKKAAEKLLG SIDVDHTQYR FGHTKVFFKA GLLGLLEEMR
DEKLASLITI TQALCRGFLK RREFQKMMER RESIYIVQYN VRSFMNVKHW PWMKLYFKIK
PLLRSAETEK EMANVKVEFA KCKEDLAKAE SKRKEMEAKM VTLLQEKNDL CLQIQTVSKI
LADECNNRLA SLSKGRIYMS KNFEKLKDNE KFYQRVINAF VRKEQMKKKL LSNIEKHDLC
VNLIVMTTVP HQPQTILGVT DTFAPISVYC DKVWTELKGQ GSRQDVMDDA SQPSSMQHSV
LVEVIEMDHL EGSLEQEKKN RLDVERAKRK LEGDLKLAQE SIMDLENDKQ QMEERLKKKD
FELSQFLAKI EDEQSVAAQS QKKIKELQAR TEELEEEIEV ERVAKSKVEK QRSDLSRELE
EISQRLEEAG GAIVAQGELN KRREAEFQKL RRDLEESTLH HEALNTALRK KHADSVAELG
EQIDNLQRVK QKLEKEKSEY KMEIDDLSGN VEVTVKSKIN FEKLCHSLED QLSDFKTKHD
ENTHLINEIN TQKAKLQNEN GEVSRLLEEK EAVLSQALRA KVAFSQQVEE LKRQIEEEAK
AKSALAHALQ SARHDCDLLR EQFEEEQEAK AELQRAMSKA NSEVAQWRVK YETDAIQRNE
ELEEAKKKLV QRLQEAEEAV KAMNAKCSSL EKTKQRLQGE VEDLMSDVER ANSQAASLDK
KQKSFDKVLS EWKQKYEEAQ AELDGSQKEL RSLNTELFKI KNSYEEALEH LEILKRENKN
LQQEISDFTE QLGENNKTLH ELEKMKKQAE SEKSELQTAL EEAEASLEHE ESKFLRVQLD
LCQVKGEVDR RLAEKDEEME QMKRNHQRVA ETLQSALDAE TRSKNDGVRI RKKMETDLNE
MEIQLSHANR QAAESQKQLK NIQAHLKEQT LNLDEALRSQ EEQREQAATM ERRSCLMQAE
VEELRAALEQ SERSRKLAEQ ELADACERAG LLHSQNTSLL NTKKKLDADM TRLQAEVEEA
VQEARNAEEK TKKAINDAAM MAEELKKEQD TSSHLERMKK NLEGSVKDLQ LRLDEAESLA
LKGGKKQLQK LEARVRELEG EVESEQKRAA DAVKGMRKYE RRAKELTYQS EEDKKSMARL
QDLADKLQLK VKAYKRQMEE AEEEASTHLA KLRKEQHELE EAQERADLAE TQVNKLRTKS
REFGKHTENI TIP
//
