ID H3D629_TETNG Unreviewed; 642 AA.
AC H3D629;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=BMP binding endothelial regulator {ECO:0000313|Ensembl:ENSTNIP00000015969.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000015969.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000015969.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H3D629; -.
DR STRING; 99883.ENSTNIP00000015969; -.
DR Ensembl; ENSTNIT00000016180.1; ENSTNIP00000015969.1; ENSTNIG00000012990.1.
DR GeneTree; ENSGT00940000156485; -.
DR HOGENOM; CLU_018024_2_0_1; -.
DR InParanoid; H3D629; -.
DR OMA; WHFANSW; -.
DR TreeFam; TF343473; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR CDD; cd19941; TIL; 1.
DR Gene3D; 6.20.200.20; -; 2.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 2.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR036084; Ser_inhib-like_sf.
DR InterPro; IPR002919; TIL_dom.
DR InterPro; IPR014853; VWF/SSPO/ZAN-like_Cys-rich_dom.
DR InterPro; IPR001007; VWF_dom.
DR InterPro; IPR001846; VWF_type-D.
DR PANTHER; PTHR46698; CROSSVEINLESS 2; 1.
DR PANTHER; PTHR46698:SF4; CROSSVEINLESS 2; 1.
DR Pfam; PF08742; C8; 1.
DR Pfam; PF01826; TIL; 1.
DR Pfam; PF00093; VWC; 2.
DR Pfam; PF00094; VWD; 1.
DR SMART; SM00832; C8; 1.
DR SMART; SM00214; VWC; 5.
DR SMART; SM00216; VWD; 1.
DR SUPFAM; SSF57603; FnI-like domain; 5.
DR SUPFAM; SSF57567; Serine protease inhibitors; 1.
DR PROSITE; PS01208; VWFC_1; 2.
DR PROSITE; PS50184; VWFC_2; 2.
DR PROSITE; PS51233; VWFD; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 121..182
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 254..313
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 317..490
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
SQ SEQUENCE 642 AA; 70962 MW; 9AE43DDB11902B16 CRC64;
GTEASCENEG EVLHIPNITD NPCITCVCLD GKADCKQEKC PLVAEDCALV VKQTGACCER
CKGCMLDGRS YNSSVSWTSS IKPCITRRCR QEGVVTEAEV QCVVHCKNPK IHPKKCCPTC
PSCIFEGHLY KEKEEFSPEG NPCIRCTCTG GRTLCVKEAC PVLSCPAHLT HTPPGQCCPR
CLGQRKVFDL SLGSCLFHSE VHENGTSFVH DDCTTCTCKD STVVCRRRCS RPGSCHGDQC
CDECLSYVKV EDVKYCRVRS KIYREGDMWS SVNCTLCACV KGSVQCRPKQ CVPISSCPSN
KILNRTGCCP VCTEKPGVCT VFGDPHYNTF DGRTFNFQGT CQYVLTRDCG GAPSDGEVLV
KNDARRTRSF SWTQSVEVRL GGLTLSLHQH LTVRRNGTRI ALPYHGPGVH IDLDGYLLKL
TTIAGLEITW DGDSFVEVVA APHLRGRLCG LCGNYNGHKR DDIMGGDGLF KFDVDEFAES
WRVEGNEVCS QQQPPRRPVS FLCHGSVKVK FRAHRECQKI KLWEFQKCHR VVDFTPFYRS
CVTDMCECPI HKNCYCESFI AYSRACEREG VSVPWKADAA CMATQCKHGA VYDTCGPGCT
KTCDNWNEIG PCHKPCVAGC HCPANLVLFQ GRCIKPTACP GR
//
