ID H3D938_TETNG Unreviewed; 325 AA.
AC H3D938;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=KH RNA binding domain containing, signal transduction associated 3 {ECO:0000313|Ensembl:ENSTNIP00000017029.1};
GN Name=KHDRBS3 {ECO:0000313|Ensembl:ENSTNIP00000017029.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000017029.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000017029.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the KHDRBS family.
CC {ECO:0000256|ARBA:ARBA00010174}.
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DR AlphaFoldDB; H3D938; -.
DR STRING; 99883.ENSTNIP00000017029; -.
DR Ensembl; ENSTNIT00000017244.1; ENSTNIP00000017029.1; ENSTNIG00000014021.1.
DR GeneTree; ENSGT00940000157280; -.
DR HOGENOM; CLU_034976_0_1_1; -.
DR InParanoid; H3D938; -.
DR OMA; QGQNSED; -.
DR TreeFam; TF314878; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR CDD; cd22384; KH-I_KHDRBS; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR InterPro; IPR045071; BBP-like.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR032571; Qua1_dom.
DR InterPro; IPR032335; Sam68-YY.
DR PANTHER; PTHR11208:SF29; KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIATED PROTEIN 3; 1.
DR PANTHER; PTHR11208; RNA-BINDING PROTEIN RELATED; 1.
DR Pfam; PF16274; Qua1; 1.
DR Pfam; PF16568; Sam68-YY; 1.
DR SMART; SM00322; KH; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 29..127
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT REGION 154..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..284
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 325 AA; 36245 MW; 5BAB041FD1A5F1DB CRC64;
VLFLEIEKTQ KDEGKEEEKF IDVVINKNMK LGQKVLIPVK QFPKFNFVGK LLGPRGNSLK
RLQEDTLTKM SILGKGSMRD KEKEEELRQS GEAKYHHLNE DLHVLIEVFA PPAEAYARMG
HALEEIKKFL IPDYNDEIRQ AQLQELTYLN GGSEEAKVPS VRGKSAVRGR GTPAPGPPRS
RGGVPPLHAA VPRGAAPRGA PPSRAASSRG RGVQRARGAP PTAGYRPAPI VQETYGEYQR
VQTSPASRPQ DYDDGYGTAY DDQGYESYDN SYNNQGQNSD DYYEYGHSGE SYDSYSVEEW
ANNRGKAPSA RATKGVYRDQ PYSRY
//
