ID H3D9A3_TETNG Unreviewed; 598 AA.
AC H3D9A3;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000017094.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000017094.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H3D9A3; -.
DR Ensembl; ENSTNIT00000017310.1; ENSTNIP00000017094.1; ENSTNIG00000014086.1.
DR GeneTree; ENSGT01070000253760; -.
DR HOGENOM; CLU_002274_3_2_1; -.
DR InParanoid; H3D9A3; -.
DR OMA; HEIMATG; -.
DR TreeFam; TF352119; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR041267; NLRP_HD2.
DR InterPro; IPR041075; NOD2_WH.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR Pfam; PF13516; LRR_6; 1.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF17776; NLRC4_HD2; 1.
DR Pfam; PF17779; NOD2_WH; 1.
DR SMART; SM00368; LRR_RI; 2.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50837; NACHT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007303}.
FT DOMAIN 1..135
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
SQ SEQUENCE 598 AA; 66438 MW; BDC420E1003E451B CRC64;
RLVLMLGVAG IGKTFSVLKF ALDWAAGLEN QDLSLVIPLS FRELNLVADG RYSLLALLRL
FHPTLAGIGA ETLAAGKLLF VFDGLDESRL SLDFSSTRVV SDAAEEASVD LLLTSLIRGN
LFPSALVWIT SRPAAASRIP PRCVDRVTEV RGFTDWQKAE YFAMRFGDEE LGGRILSHMK
TCRSLHIMCQ VPVFCWITAT VLKHMFSTDK GGEPPKTLTD MFSHFLLVQT RMKKQKYGEG
EEAGPQELAE SDRGHLVKLG RLAFESLEKG NVAFYQEDLE QCGLDAQEVL VYSGVCTEVF
KEESVIFQKS VYCFVHLSVQ EFLAAVYMFQ CFTSRNTQVL HAFLQTDVSD LSAFLREATM
KSFESKNGHL DLFVRFLHGL ALETNQRILG GLLGPTDNSR ESVADAIANL KQMKSADIPP
DRSINIFHCL MEINDLSIHQ DIQDFLGSRN QSETTLTEVH CSALAYMLQM SESVLEELNL
EKYNASMGGR QRLVPAVRNC RRARLSNSRL CDVHCEVVAS ALRSSPSHLR ELEMSVNHLQ
DSGAQLLCAG LLPQSPLETL RLRGCSLSGD SCTSLASALR AKPDPSHLRE LELSYNKL
//
