ID H3DB97_TETNG Unreviewed; 416 AA.
AC H3DB97;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=DNA-damage inducible protein 2 {ECO:0000313|Ensembl:ENSTNIP00000017789.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000017789.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000017789.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the DDI1 family.
CC {ECO:0000256|ARBA:ARBA00009136}.
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DR AlphaFoldDB; H3DB97; -.
DR STRING; 99883.ENSTNIP00000017789; -.
DR Ensembl; ENSTNIT00000018013.1; ENSTNIP00000017789.1; ENSTNIG00000014752.1.
DR GeneTree; ENSGT00950000182999; -.
DR HOGENOM; CLU_020435_1_0_1; -.
DR InParanoid; H3DB97; -.
DR OMA; QIGNDHL; -.
DR TreeFam; TF333421; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd05479; RP_DDI; 1.
DR CDD; cd01796; Ubl_Ddi1_like; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR InterPro; IPR033882; DDI1_N.
DR InterPro; IPR019103; Peptidase_aspartic_DDI1-type.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR15397:SF3; DNA DAMAGE-INDUCIBLE 1 HOMOLOG 2; 1.
DR PANTHER; PTHR15397; SODIUM-GLUCOSE COTRANSPORTER REGULATORY PROTEIN -RELATED; 1.
DR Pfam; PF09668; Asp_protease; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50053; UBIQUITIN_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303}.
FT DOMAIN 27..81
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000259|PROSITE:PS50053"
FT REGION 76..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..118
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..133
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 416 AA; 46026 MW; 4729929EA9D9C9DE CRC64;
MLVTVFCAPR DRPETTFDLH VSPDLVLRDF VVLCVTESGI PADEIQITYA DQPLKDPTRA
LGTYGVKDGD VVVLRQTDRR PLPPQPAFPG LPRIDFRSIS VPGTSSSASP RTATRPQPPA
SLGQPPLQRA PQPSVPGAFP GNSPQGLDDP ALLQQMLLSN PHELSLLKER NPPLAEALLS
GDLERFTKVL MEQQQDRAKR EQERIRLLTA DPFDLEAQAK IEEDIRQHNV EENMTIAMEE
APESFGQVVM LYINCKVNGH PVKAFVDSGA QMTIMSQACA ERCNIMRLVD RRWAGIAKGV
GTQKIIGRVH LAQVQIEGDF LPCSFSILED QPMDMLLGLD MLKRHQCSID LKKNVLLIGT
TGTETRFLSE AELPECARLA YGAEGREDVR PDELADRELA EALQRSIQES GEKRSA
//
